[Spontaneous and DL-penicillamine-induced renal copper excretion in liver diseases (author's transl)]. 1979

K Friedrich, and H Henning

The levels of cupriuresis before and after DL-Penicillamine have been investigated in 168 cases. The mean copper excretion before Penicillamine in chronic activ liver disease, chronic persistant hepatitis, cirrhosis and in transitional cases of aggressiv chronic hepatitis and primary biliary cirrhosis ranged from 29 gamma to 48 gamma/24 hr.; however, in some cases the daily copper excretion exceeds 100 gamma, as well in subjects with liver disease as in normals too. After ingesting 900 mg DL-Penicillamine the mean values of cupriuresis ranged from 500 gamma to 600 gamma/24 hr. Abnormal results were found in about 15% of those subjects with liver diseases; in only two of 20 cases with hypercupruria after Penicillamine Wilson's Disease was established.

UI MeSH Term Description Entries
D008103 Liver Cirrhosis Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. Cirrhosis, Liver,Fibrosis, Liver,Hepatic Cirrhosis,Liver Fibrosis,Cirrhosis, Hepatic
D008107 Liver Diseases Pathological processes of the LIVER. Liver Dysfunction,Disease, Liver,Diseases, Liver,Dysfunction, Liver,Dysfunctions, Liver,Liver Disease,Liver Dysfunctions
D010396 Penicillamine 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease. Dimethylcysteine,Mercaptovaline,beta,beta-Dimethylcysteine,Copper Penicillaminate,Cuprenil,Cuprimine,D-3-Mercaptovaline,D-Penicillamine,Metalcaptase,D 3 Mercaptovaline,D Penicillamine,Penicillaminate, Copper,beta,beta Dimethylcysteine
D003300 Copper A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. Copper-63,Copper 63
D006505 Hepatitis INFLAMMATION of the LIVER. Hepatitides
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

K Friedrich, and H Henning
December 1974, Deutsche medizinische Wochenschrift (1946),
K Friedrich, and H Henning
June 1979, Medizinische Klinik,
K Friedrich, and H Henning
August 1978, Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis,
K Friedrich, and H Henning
January 1974, Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie,
K Friedrich, and H Henning
July 1979, Lijecnicki vjesnik,
K Friedrich, and H Henning
July 1974, Casopis lekaru ceskych,
K Friedrich, and H Henning
July 1976, Deutsche medizinische Wochenschrift (1946),
K Friedrich, and H Henning
January 1967, Polski tygodnik lekarski (Warsaw, Poland : 1960),
K Friedrich, and H Henning
May 1979, MMW, Munchener medizinische Wochenschrift,
Copied contents to your clipboard!