BIOMAT Database Logo BIOMAT Database Logo

[Mechanism of the antineoplastic action of the inhibitor of free radical processes 2,6-di-tert-butyl-4-methylphenol (ionol)]. 1973

N M Emanuél', and A N Saprin, and T S Shuliakovskaia, and L N Kozlova, and T V Bunto

UI MeSH Term Description Entries
D008113 Liver Neoplasms Tumors or cancer of the LIVER. Cancer of Liver,Hepatic Cancer,Liver Cancer,Cancer of the Liver,Cancer, Hepatocellular,Hepatic Neoplasms,Hepatocellular Cancer,Neoplasms, Hepatic,Neoplasms, Liver,Cancer, Hepatic,Cancer, Liver,Cancers, Hepatic,Cancers, Hepatocellular,Cancers, Liver,Hepatic Cancers,Hepatic Neoplasm,Hepatocellular Cancers,Liver Cancers,Liver Neoplasm,Neoplasm, Hepatic,Neoplasm, Liver
D008297 Male Males
D009374 Neoplasms, Experimental Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms. Experimental Neoplasms,Experimental Neoplasm,Neoplasm, Experimental
D010636 Phenols Benzene derivatives that include one or more hydroxyl groups attached to the ring structure.
D004124 p-Dimethylaminoazobenzene A reagent used mainly to induce experimental liver cancer. According to the Fourth Annual Report on Carcinogens (NTP 85-002, p. 89) published in 1985, this compound "may reasonably be anticipated to be a carcinogen." (Merck, 11th ed) Butter Yellow,Dimethylaminoazobenzene,4-Dimethylaminoazobenzene,Methyl Yellow,p-Dimethylaminoazobenzene, (E)-Isomer,p-Dimethylaminoazobenzene, (Z)-Isomer,4 Dimethylaminoazobenzene,p Dimethylaminoazobenzene
D004578 Electron Spin Resonance Spectroscopy A technique applicable to the wide variety of substances which exhibit paramagnetism because of the magnetic moments of unpaired electrons. The spectra are useful for detection and identification, for determination of electron structure, for study of interactions between molecules, and for measurement of nuclear spins and moments. (From McGraw-Hill Encyclopedia of Science and Technology, 7th edition) Electron nuclear double resonance (ENDOR) spectroscopy is a variant of the technique which can give enhanced resolution. Electron spin resonance analysis can now be used in vivo, including imaging applications such as MAGNETIC RESONANCE IMAGING. ENDOR,Electron Nuclear Double Resonance,Electron Paramagnetic Resonance,Paramagnetic Resonance,Electron Spin Resonance,Paramagnetic Resonance, Electron,Resonance, Electron Paramagnetic,Resonance, Electron Spin,Resonance, Paramagnetic
D005609 Free Radicals Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. Free radicals include reactive oxygen and nitrogen species (RONS). They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated. Free Radical
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000970 Antineoplastic Agents Substances that inhibit or prevent the proliferation of NEOPLASMS. Anticancer Agent,Antineoplastic,Antineoplastic Agent,Antineoplastic Drug,Antitumor Agent,Antitumor Drug,Cancer Chemotherapy Agent,Cancer Chemotherapy Drug,Anticancer Agents,Antineoplastic Drugs,Antineoplastics,Antitumor Agents,Antitumor Drugs,Cancer Chemotherapy Agents,Cancer Chemotherapy Drugs,Chemotherapeutic Anticancer Agents,Chemotherapeutic Anticancer Drug,Agent, Anticancer,Agent, Antineoplastic,Agent, Antitumor,Agent, Cancer Chemotherapy,Agents, Anticancer,Agents, Antineoplastic,Agents, Antitumor,Agents, Cancer Chemotherapy,Agents, Chemotherapeutic Anticancer,Chemotherapy Agent, Cancer,Chemotherapy Agents, Cancer,Chemotherapy Drug, Cancer,Chemotherapy Drugs, Cancer,Drug, Antineoplastic,Drug, Antitumor,Drug, Cancer Chemotherapy,Drug, Chemotherapeutic Anticancer,Drugs, Antineoplastic,Drugs, Antitumor,Drugs, Cancer Chemotherapy
D000975 Antioxidants Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. Anti-Oxidant,Antioxidant,Antioxidant Activity,Endogenous Antioxidant,Endogenous Antioxidants,Anti-Oxidant Effect,Anti-Oxidant Effects,Anti-Oxidants,Antioxidant Effect,Antioxidant Effects,Activity, Antioxidant,Anti Oxidant,Anti Oxidant Effect,Anti Oxidant Effects,Anti Oxidants,Antioxidant, Endogenous,Antioxidants, Endogenous

Related Publications

N M Emanuél', and A N Saprin, and T S Shuliakovskaia, and L N Kozlova, and T V Bunto
[Effect of ionol (2,6-di-tert-butyl-4-methylphenol) on the duration of life of Drosophila melanogaster].
January 1971, Biulleten' eksperimental'noi biologii i meditsiny,
N M Emanuél', and A N Saprin, and T S Shuliakovskaia, and L N Kozlova, and T V Bunto
[Kinetics of the introduction and elimination of 2,6-di-tert butyl-4-methylphenol in humans].
January 1969, Izvestiia Akademii nauk SSSR. Seriia biologicheskaia,
N M Emanuél', and A N Saprin, and T S Shuliakovskaia, and L N Kozlova, and T V Bunto
Free radical intermediates during peroxidase oxidation of 2-t-butyl-4-methoxyphenol, 2,6-di-t-butyl-4-methylphenol, and related phenol compounds.
March 1989, Archives of biochemistry and biophysics,
N M Emanuél', and A N Saprin, and T S Shuliakovskaia, and L N Kozlova, and T V Bunto
Immunochemical visualization and identification of rat liver proteins adducted by 2,6-di-tert-butyl-4-methylphenol (BHT).
October 1997, Chemical research in toxicology,
N M Emanuél', and A N Saprin, and T S Shuliakovskaia, and L N Kozlova, and T V Bunto
Alkylation of 2'-deoxynucleosides and DNA by quinone methides derived from 2,6-di-tert-butyl-4-methylphenol.
December 1996, Chemical research in toxicology,
N M Emanuél', and A N Saprin, and T S Shuliakovskaia, and L N Kozlova, and T V Bunto
Decomposition of vitamin D by the hydroperoxide formed from 2,6-di-tert-butyl-4-methylphenol during alkali saponification.
June 1970, The Journal of vitaminology,
N M Emanuél', and A N Saprin, and T S Shuliakovskaia, and L N Kozlova, and T V Bunto
Toxicity of 2,6-Di-tert-butyl-4-Nitrophenol (DBNP).
April 2001, Applied occupational and environmental hygiene,
N M Emanuél', and A N Saprin, and T S Shuliakovskaia, and L N Kozlova, and T V Bunto
2,6-Di-tert-butyl-4-(morpholinometh-yl)-phenol monohydrate.
January 2008, Acta crystallographica. Section E, Structure reports online,
N M Emanuél', and A N Saprin, and T S Shuliakovskaia, and L N Kozlova, and T V Bunto
2,6-Di-tert-butyl-4-(methoxy-meth-yl)phenol.
February 2008, Acta crystallographica. Section E, Structure reports online,
N M Emanuél', and A N Saprin, and T S Shuliakovskaia, and L N Kozlova, and T V Bunto
Antiinflammatory 2,6-di-tert-butyl-4-(2-arylethenyl)phenols.
January 1989, Journal of medicinal chemistry,
Copied contents to your clipboard!