Late deaths after resection for bronchial carcinoma. 1979

J R Belcher, and M Rehahn

1267 patients who underwent surgical treatment for bronchial carcinoma during the period 1949--70 have been studied. 304 underwent thoracotomy without further resection; 88% died within 12 months; the maximum survival was 56 months. Of the remaining 963 patients, 869 late deaths are recorded, and the causes of these have been studied. The 5-year actuarial survival rate was 25.9%; the 10-year rate 15.3%; the 15-year rate 9.3%; and the 20-year rate 3.9%. 610 of the 869 deaths were due to bronchial carcinoma; 79 were due to respiratory disease; 57 to coronary disease; and 23 to other neoplasms. The percentage of total deaths due to bronchial carcinoma declined with the passage of time. It was 86.5% during the first year; 79.2% during the next 4 years; 53.7% from 5 to 10 years; and 39.3% over 10 years. The second commonest cause of death was respiratory disease, which tended to be related to the extent of resection. Compared with a population of the same age and sex structure, suffering the death rates of England and Wales during the period involved, these patients show a massive excess of deaths from bronchial carcinoma and a smaller excess from respiratory disease; and a considerable shortfall from coronary disease, other carcinomas, and all other causes. A more favourable probability of survival was linked with lobectomy, squamous cell type and the younger age group. A less favourable probability was linked with pneumonectomy, adenocarcinoma and older age-groups. There was no significant difference due to sex. After the first 2 years, with their heavy death rate, the chances of surviving to 10 years improved by about 15% each year.

UI MeSH Term Description Entries
D008297 Male Males
D008722 Methods A series of steps taken in order to conduct research. Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D012140 Respiratory Tract Diseases Diseases involving the RESPIRATORY SYSTEM. Respiratory Diseases,Respiratory System Diseases,Disease, Respiratory System,Disease, Respiratory Tract,Respiratory System Disease,Respiratory Tract Disease
D001984 Bronchial Neoplasms Tumors or cancer of the BRONCHI. Neoplasms, Bronchial,Bronchial Neoplasm,Neoplasm, Bronchial
D003327 Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. Coronary Heart Disease,Coronary Diseases,Coronary Heart Diseases,Disease, Coronary,Disease, Coronary Heart,Diseases, Coronary,Diseases, Coronary Heart,Heart Disease, Coronary,Heart Diseases, Coronary
D004739 England A part of Great Britain within the United Kingdom.
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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