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Outpatient detoxification of heroin addiction, 1969--1973 (methadone, darvon, codeine, clonidine). 1979

R T Rappolt, and F Lawrence

UI MeSH Term Description Entries
D008691 Methadone A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3) Amidone,Biodone,Dolophine,Metadol,Metasedin,Methaddict,Methadone Hydrochloride,Methadose,Methex,Phenadone,Phymet,Physeptone,Pinadone,Symoron,Hydrochloride, Methadone
D011431 Dextropropoxyphene A narcotic analgesic structurally related to METHADONE. Only the dextro-isomer has an analgesic effect; the levo-isomer appears to exert an antitussive effect. D-Propoxyphene,Darvon,Propoxyphene,Propoxyphene Hydrochloride,Propoxyphene Hydrochloride, (R*,R*)-(+-)-Isomer,Propoxyphene Hydrochloride, (R-(R*,R*))-Isomer,Propoxyphene Hydrochloride, (R-(R*,S*))-Isomer,Propoxyphene Hydrochloride, (S-(R*,R*))-Isomer,Propoxyphene Maleate, (+)-Isomer,Propoxyphene Phosphate, (S-(R*,S*))-Isomer,Propoxyphene Sulfate, (S-(R*,S*))-Isomer,D Propoxyphene,Hydrochloride, Propoxyphene
D003000 Clonidine An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION. Catapres,Catapresan,Catapressan,Chlophazolin,Clofelin,Clofenil,Clonidine Dihydrochloride,Clonidine Hydrochloride,Clonidine Monohydrobromide,Clonidine Monohydrochloride,Clopheline,Dixarit,Gemiton,Hemiton,Isoglaucon,Klofelin,Klofenil,M-5041T,ST-155,Dihydrochloride, Clonidine,Hydrochloride, Clonidine,M 5041T,M5041T,Monohydrobromide, Clonidine,Monohydrochloride, Clonidine,ST 155,ST155
D003061 Codeine An opioid analgesic related to MORPHINE but with less potent analgesic properties and mild sedative effects. It also acts centrally to suppress cough. Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-,Ardinex,Codeine Phosphate,Isocodeine,N-Methylmorphine,N Methylmorphine
D006556 Heroin Dependence Strong dependence or addiction, both physiological and emotional, upon HEROIN. Heroin Abuse,Heroin Addiction,Heroin Smoking,Abuse, Heroin,Addiction, Heroin,Dependence, Heroin,Heroin Smokings,Smoking, Heroin
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

R T Rappolt, and F Lawrence
Clonidine in outpatient detoxification from methadone maintenance.
April 1985, Archives of general psychiatry,
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Outpatient induction to methadone maintenance treatment for heroin addiction.
May 1971, Archives of internal medicine,
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Clonidine vs. methadone for opiate detoxification: double-blind outpatient trials.
February 1981, NIDA research monograph,
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Slow detoxification in heroin addiction. Combined use of methadone and psychotherapy.
December 1972, New York state journal of medicine,
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Outpatient clonidine detoxification.
March 1981, Lancet (London, England),
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Methadone management of heroin addiction.
June 1970, Bulletin of the New York Academy of Medicine,
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Methadone treatment of heroin addiction.
January 1973, Annual review of medicine,
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Clonidine is not a useful adjunct to methadone gradual detoxification in opioid addiction.
September 1994, The British journal of psychiatry : the journal of mental science,
R T Rappolt, and F Lawrence
Clonidine versus methadone for opiate detoxification.
December 1980, Lancet (London, England),
R T Rappolt, and F Lawrence
Efficacy of clonidine and of methadone in the rapid detoxification of patients dependent on heroin.
September 1985, Clinical pharmacology and therapeutics,
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