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Kinetic approach to the development in beta-lactam antibiotics. I. Comparative stability of semisynthetic penicllins and 6-aminopenicillanic acid in aqueous solution. 1974

T Yamana, and A Tsuji, and Y Mizukami

UI MeSH Term Description Entries
D007700 Kinetics The rate dynamics in chemical or physical systems.
D010397 Penicillanic Acid A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed) Acid, Penicillanic
D010406 Penicillins A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065) Antibiotics, Penicillin,Penicillin,Penicillin Antibiotics
D004355 Drug Stability The chemical and physical integrity of a pharmaceutical product. Drug Shelf Life,Drugs Shelf Lives,Shelf Life, Drugs,Drug Stabilities,Drugs Shelf Life,Drugs Shelf Live,Life, Drugs Shelf,Shelf Life, Drug,Shelf Live, Drugs,Shelf Lives, Drugs
D006868 Hydrolysis The process of cleaving a chemical compound by the addition of a molecule of water.

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