BIOMAT Database Logo BIOMAT Database Logo

Proceedings: Human placental oestradiol-17beta dehydrogenase affinity labelled at the active region. 1974

L L Engel, and R M Schultz, and E V Groman

UI MeSH Term Description Entries
D009243 NAD A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) Coenzyme I,DPN,Diphosphopyridine Nucleotide,Nadide,Nicotinamide-Adenine Dinucleotide,Dihydronicotinamide Adenine Dinucleotide,NADH,Adenine Dinucleotide, Dihydronicotinamide,Dinucleotide, Dihydronicotinamide Adenine,Dinucleotide, Nicotinamide-Adenine,Nicotinamide Adenine Dinucleotide,Nucleotide, Diphosphopyridine
D010920 Placenta A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES). Placentoma, Normal,Placentome,Placentas,Placentomes
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D004958 Estradiol The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. 17 beta-Estradiol,Estradiol-17 beta,Oestradiol,17 beta-Oestradiol,Aerodiol,Delestrogen,Estrace,Estraderm TTS,Estradiol Anhydrous,Estradiol Hemihydrate,Estradiol Hemihydrate, (17 alpha)-Isomer,Estradiol Monohydrate,Estradiol Valerate,Estradiol Valeriante,Estradiol, (+-)-Isomer,Estradiol, (-)-Isomer,Estradiol, (16 alpha,17 alpha)-Isomer,Estradiol, (16 alpha,17 beta)-Isomer,Estradiol, (17-alpha)-Isomer,Estradiol, (8 alpha,17 beta)-(+-)-Isomer,Estradiol, (8 alpha,17 beta)-Isomer,Estradiol, (9 beta,17 alpha)-Isomer,Estradiol, (9 beta,17 beta)-Isomer,Estradiol, Monosodium Salt,Estradiol, Sodium Salt,Estradiol-17 alpha,Estradiol-17beta,Ovocyclin,Progynon-Depot,Progynova,Vivelle,17 beta Estradiol,17 beta Oestradiol,Estradiol 17 alpha,Estradiol 17 beta,Estradiol 17beta,Progynon Depot
D004970 Estrone An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women. Folliculin (Hormone),Estrone, (+-)-Isomer,Estrone, (8 alpha)-Isomer,Estrone, (9 beta)-Isomer,Estrovarin,Kestrone,Unigen,Wehgen
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006913 Hydroxysteroid Dehydrogenases Enzymes of the oxidoreductase class that catalyze the dehydrogenation of hydroxysteroids. (From Enzyme Nomenclature, 1992) EC 1.1.-. Hydroxysteroid Dehydrogenase,Dehydrogenase, Hydroxysteroid,Dehydrogenases, Hydroxysteroid
D001665 Binding Sites The parts of a macromolecule that directly participate in its specific combination with another molecule. Combining Site,Binding Site,Combining Sites,Site, Binding,Site, Combining,Sites, Binding,Sites, Combining
D013329 Structure-Activity Relationship The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups. Relationship, Structure-Activity,Relationships, Structure-Activity,Structure Activity Relationship,Structure-Activity Relationships

Related Publications

L L Engel, and R M Schultz, and E V Groman
Affinity labelling of the active site of the 17beta-oestradiol dehydrogenase of human placental cytosol.
April 1973, FEBS letters,
L L Engel, and R M Schultz, and E V Groman
Nucleotides and human placental oestradiol-17beta dehydrogenase.
January 1976, Biochemical Society transactions,
L L Engel, and R M Schultz, and E V Groman
Influence of magnesium sulphate on the inhibition of human placental oestradiol-17beta dehydrogenase by adenosine triphosphate [proceedings].
January 1978, Biochemical Society transactions,
L L Engel, and R M Schultz, and E V Groman
Inhibition of human placental oestradiol-17beta dehydrogenase by adenosine triphosphate: the importance of the coenzyme.
January 1976, Biochemical Society transactions,
L L Engel, and R M Schultz, and E V Groman
I. Affinity labelling of an histidine of the active site of the human placental 17 beta-oestradiol dehydrogenase.
October 1973, FEBS letters,
L L Engel, and R M Schultz, and E V Groman
Proceedings: The relationship between oestradiol-17beta receptor concentration and endogenous oestradiol-17beta in human breast tumour tissue.
November 1974, The Journal of endocrinology,
L L Engel, and R M Schultz, and E V Groman
Letter: Oestradiol 17beta: inhibitor of placental growth.
July 1974, Lancet (London, England),
L L Engel, and R M Schultz, and E V Groman
NAD(P)+ analogues: tools for the investigation of the active site of oestradiol 17beta-dehydrogenase from human placenta.
August 1975, European journal of biochemistry,
L L Engel, and R M Schultz, and E V Groman
Proceedings: Measurement of unconjugated oestradiol-17beta in human urine by radioimmunoassay.
May 1974, The Journal of endocrinology,
L L Engel, and R M Schultz, and E V Groman
Human placental 17beta-estradiol dehydrogenase: characterization and structural studies.
January 1974, Recent progress in hormone research,
Copied contents to your clipboard!