| D007108 |
Immune Tolerance |
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc. |
Immunosuppression (Physiology),Immunosuppressions (Physiology),Tolerance, Immune |
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| D008198 |
Lymph Nodes |
They are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system. |
Lymph Node,Node, Lymph,Nodes, Lymph |
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| D008214 |
Lymphocytes |
White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS. |
Lymphoid Cells,Cell, Lymphoid,Cells, Lymphoid,Lymphocyte,Lymphoid Cell |
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| D011828 |
Radiation Chimera |
An organism whose body contains cell populations of different genotypes as a result of the TRANSPLANTATION of donor cells after sufficient ionizing radiation to destroy the mature recipient's cells which would otherwise reject the donor cells. |
Chimera, Radiation,Chimeras, Radiation,Radiation Chimeras |
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| D001853 |
Bone Marrow |
The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells. |
Marrow,Red Marrow,Yellow Marrow,Marrow, Bone,Marrow, Red,Marrow, Yellow |
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| D004920 |
Erythropoiesis |
The production of red blood cells (ERYTHROCYTES). In humans, erythrocytes are produced by the YOLK SAC in the first trimester; by the liver in the second trimester; by the BONE MARROW in the third trimester and after birth. In normal individuals, the erythrocyte count in the peripheral blood remains relatively constant implying a balance between the rate of erythrocyte production and rate of destruction. |
Erythropoieses |
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| D005260 |
Female |
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Females |
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| D006087 |
Graft vs Host Reaction |
An immunological attack mounted by a graft against the host because of HISTOINCOMPATIBILITY when immunologically competent cells are transplanted to an immunologically incompetent host; the resulting clinical picture is that of GRAFT VS HOST DISEASE. |
HLA Sensitization,Human Leukocyte Antigen Sensitization,Sensitization, HLA |
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| D006410 |
Hematopoiesis |
The development and formation of various types of BLOOD CELLS. Hematopoiesis can take place in the BONE MARROW (medullary) or outside the bone marrow (HEMATOPOIESIS, EXTRAMEDULLARY). |
Hematopoiesis, Medullary,Haematopoiesis,Medullary Hematopoiesis |
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| D000469 |
Alkaline Phosphatase |
An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1. |
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