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A double-blind placebo-controlled multicentre study with ritodrine, a beta-mimetic uterine relaxant, has been performed in 91 patients in premature labour. All patients were treated according to a fixed dosage scheme consisting of an intravenous infusion followed by oral tablets for a total of seven days. Ritodrine arrested premature labour in 80%, the placebo in 48% of the patients (P=0.02). This short treatment, however, was usually not sufficient to prolong gestation till term. Apart from a slight to moderate rise in maternal heart rate and a slight rise in systolic blood pressure, ritodrine did not give rise to any maternal or fetal side effects. The problems of patient selection and of evaluation of the results are discussed.
A Wesselius-de Casparis, and
M Thiery, and
A Yo le Sian, and
K Baumgarten, and
I Brosens, and
O Gamisans, and
J G Stolk, and
W Vivier
April 1977,
British medical journal,
A Wesselius-de Casparis, and
M Thiery, and
A Yo le Sian, and
K Baumgarten, and
I Brosens, and
O Gamisans, and
J G Stolk, and
W Vivier
March 1974,
The Journal of obstetrics and gynaecology of the British Commonwealth,
A Wesselius-de Casparis, and
M Thiery, and
A Yo le Sian, and
K Baumgarten, and
I Brosens, and
O Gamisans, and
J G Stolk, and
W Vivier
September 1978,
British medical journal,
A Wesselius-de Casparis, and
M Thiery, and
A Yo le Sian, and
K Baumgarten, and
I Brosens, and
O Gamisans, and
J G Stolk, and
W Vivier
July 1996,
British journal of obstetrics and gynaecology,
A Wesselius-de Casparis, and
M Thiery, and
A Yo le Sian, and
K Baumgarten, and
I Brosens, and
O Gamisans, and
J G Stolk, and
W Vivier
February 1967,
The Journal of obstetrics and gynaecology of the British Commonwealth,
A Wesselius-de Casparis, and
M Thiery, and
A Yo le Sian, and
K Baumgarten, and
I Brosens, and
O Gamisans, and
J G Stolk, and
W Vivier
January 1977,
British journal of obstetrics and gynaecology,
A Wesselius-de Casparis, and
M Thiery, and
A Yo le Sian, and
K Baumgarten, and
I Brosens, and
O Gamisans, and
J G Stolk, and
W Vivier
January 1969,
Acta anaesthesiologica Scandinavica. Supplementum,
A Wesselius-de Casparis, and
M Thiery, and
A Yo le Sian, and
K Baumgarten, and
I Brosens, and
O Gamisans, and
J G Stolk, and
W Vivier
January 2004,
Lancet (London, England),
A Wesselius-de Casparis, and
M Thiery, and
A Yo le Sian, and
K Baumgarten, and
I Brosens, and
O Gamisans, and
J G Stolk, and
W Vivier
May 2005,
The Journal of pediatrics,
A Wesselius-de Casparis, and
M Thiery, and
A Yo le Sian, and
K Baumgarten, and
I Brosens, and
O Gamisans, and
J G Stolk, and
W Vivier
November 2006,
BJOG : an international journal of obstetrics and gynaecology,
