Biomaterial Database

[Arsenical peripheral polyneuropathy: treatment with penicillamine. Determination of inorganic arsenic in peripheral nerve, blood and urine]. 1974

A Anghinah, and H M Canelas, and F Bastos de Jorge, and F Forti

UI	MeSH Term	Description	Entries
D010396	Penicillamine	3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.	Dimethylcysteine,Mercaptovaline,beta,beta-Dimethylcysteine,Copper Penicillaminate,Cuprenil,Cuprimine,D-3-Mercaptovaline,D-Penicillamine,Metalcaptase,D 3 Mercaptovaline,D Penicillamine,Penicillaminate, Copper,beta,beta Dimethylcysteine
D010525	Peripheral Nerves	The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.	Endoneurium,Epineurium,Perineurium,Endoneuriums,Epineuriums,Nerve, Peripheral,Nerves, Peripheral,Perineuriums,Peripheral Nerve
D011041	Poisoning	A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent.	Poisonings
D011115	Polyneuropathies	Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.	Polyneuropathy, Acquired,Polyneuropathy, Critical Illness,Polyneuropathy, Familial,Polyneuropathy, Inherited,Polyneuropathy, Motor,Acquired Polyneuropathies,Acquired Polyneuropathy,Critical Illness Polyneuropathies,Critical Illness Polyneuropathy,Familial Polyneuropathies,Familial Polyneuropathy,Inherited Polyneuropathies,Inherited Polyneuropathy,Motor Polyneuropathies,Motor Polyneuropathy,Polyneuropathies, Acquired,Polyneuropathies, Critical Illness,Polyneuropathies, Familial,Polyneuropathies, Inherited,Polyneuropathies, Motor,Polyneuropathy
D002214	Capsules	Hard or soft soluble containers used for the oral administration of medicine.	Capsule,Microcapsule,Microcapsules
D004341	Drug Evaluation	Any process by which toxicity, metabolism, absorption, elimination, preferred route of administration, safe dosage range, etc., for a drug or group of drugs is determined through clinical assessment in humans or veterinary animals.	Evaluation Studies, Drug,Drug Evaluation Studies,Drug Evaluation Study,Drug Evaluations,Evaluation Study, Drug,Evaluation, Drug,Evaluations, Drug,Studies, Drug Evaluation,Study, Drug Evaluation
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001151	Arsenic	A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)	Arsenic-75,Arsenic 75
D020261	Arsenic Poisoning	Disorders associated with acute or chronic exposure to compounds containing ARSENIC (ARSENICALS) which may be fatal. Acute oral ingestion is associated with gastrointestinal symptoms and an encephalopathy which may manifest as SEIZURES, mental status changes, and COMA. Chronic exposure is associated with mucosal irritation, desquamating rash, myalgias, peripheral neuropathy, and white transverse (Mees) lines in the fingernails. (Adams et al., Principles of Neurology, 6th ed, p1212)	Arsenic Encephalopathy,Arsenic Induced Polyneuropathy,Arsenic Poisoning, Inorganic,Arsenic Poisoning, Nervous System,Arsenic Poisoning, Organic,Encephalopathy, Arsenic,Inorganic Arsenic Poisoning,Nervous System Poisoning, Arsenic,Nervous System, Organic Arsenic Poisoning,Neurotoxicity Syndrome, Arsenical,Organic Arsenic Poisoning, Nervous System,Poisoning, Arsenic, Nervous System,Polyneuropathy, Arsenic-Induced,Arsenic Encephalopathies,Arsenic Poisonings,Arsenic Poisonings, Inorganic,Arsenic Poisonings, Organic,Arsenic-Induced Polyneuropathies,Arsenic-Induced Polyneuropathy,Arsenical Neurotoxicity Syndrome,Arsenical Neurotoxicity Syndromes,Encephalopathies, Arsenic,Inorganic Arsenic Poisonings,Neurotoxicity Syndromes, Arsenical,Organic Arsenic Poisoning,Organic Arsenic Poisonings,Poisoning, Arsenic,Poisoning, Inorganic Arsenic,Poisoning, Organic Arsenic,Poisonings, Arsenic,Poisonings, Inorganic Arsenic,Poisonings, Organic Arsenic,Polyneuropathy, Arsenic Induced,Syndrome, Arsenical Neurotoxicity,Syndromes, Arsenical Neurotoxicity