Biomaterial Database

[The endocrine function of the pancreas: insulin and glucagon, their biosynthesis, secretion and metabolic role]. 1974

Z Szybiński

UI	MeSH Term	Description	Entries
D007328	Insulin	A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).	Iletin,Insulin A Chain,Insulin B Chain,Insulin, Regular,Novolin,Sodium Insulin,Soluble Insulin,Chain, Insulin B,Insulin, Sodium,Insulin, Soluble,Regular Insulin
D010179	Pancreas	A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.
D005934	Glucagon	A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511)	Glucagon (1-29),Glukagon,HG-Factor,Hyperglycemic-Glycogenolytic Factor,Proglucagon (33-61),HG Factor,Hyperglycemic Glycogenolytic Factor
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000078790	Insulin Secretion	Production and release of insulin from PANCREATIC BETA CELLS that primarily occurs in response to elevated BLOOD GLUCOSE levels.	Secretion, Insulin

Related Publications

Z Szybiński

[Glucagon and endocrine pancreas secretion].

September 1962, Nihon Naibunpi Gakkai zasshi,

Z Szybiński

Glucagon gene expression in the endocrine pancreas: the role of the transcription factor Pax6 in α-cell differentiation, glucagon biosynthesis and secretion.

October 2011, Diabetes, obesity & metabolism,

Z Szybiński

[Insulin and glucagon secretion of the preserved dog pancreas].

January 1986, Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR,

Z Szybiński

Secretory regulation of endocrine pancreas: Cyclic AMP and glucagon secretion.

July 1975, The Journal of clinical endocrinology and metabolism,

Z Szybiński

Endocrine function of pancreas transplant: insulin, glucagon and somatostatin release from rat pancreatic isograft.

January 1982, The Japanese journal of surgery,

Z Szybiński

Prolactin and the secretion of insulin and glucagon by the pancreas.

September 1955, The American journal of physiology,

Z Szybiński

[Insulin biosynthesis, storage and secretion. 12. Biogenic mono-amines in the endocrine pancreas of guinea pigs].

September 1968, Lakartidningen,