Infectious mononucleosis with severe neutropenia and opsonic antineutrophil activity. 1979

D L Stevens, and E D Everett, and L A Boxer, and R A Landefeld

Severe granulocytopenia is an uncommon complication of infectious mononucleosis, only 18 cases having been reported previously. Our review and experience with this case would indicate that (1) severe granulocytopenia is usually diagnosed at about the third or fourth week of illness, (2) bone marrow examination most commonly reveals lack of mature neutrophil precursors in the myelocytic series, (3) the duration of usually short, lasting about a week, and (4) most patients recover without treatment. The laboratory findings in our case suggests that the neutropenia may be antibody mediated.

UI MeSH Term Description Entries
D007244 Infectious Mononucleosis A common, acute infection usually caused by the Epstein-Barr virus (HERPESVIRUS 4, HUMAN). There is an increase in mononuclear white blood cells and other atypical lymphocytes, generalized lymphadenopathy, splenomegaly, and occasionally hepatomegaly with hepatitis. Glandular Fever,Mononucleosis, Infectious,Fever, Glandular
D007958 Leukocyte Count The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells. Blood Cell Count, White,Differential Leukocyte Count,Leukocyte Count, Differential,Leukocyte Number,White Blood Cell Count,Count, Differential Leukocyte,Count, Leukocyte,Counts, Differential Leukocyte,Counts, Leukocyte,Differential Leukocyte Counts,Leukocyte Counts,Leukocyte Counts, Differential,Leukocyte Numbers,Number, Leukocyte,Numbers, Leukocyte
D008297 Male Males
D009503 Neutropenia A decrease in the number of NEUTROPHILS found in the blood. Neutropenias
D009895 Opsonin Proteins Proteins that bind to particles and cells to increase susceptibility to PHAGOCYTOSIS, especially ANTIBODIES bound to EPITOPES that attach to FC RECEPTORS. COMPLEMENT C3B may also participate. Opsonin,Opsonin Protein,Opsonins,Protein, Opsonin
D010084 Oxidation-Reduction A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471). Redox,Oxidation Reduction
D005947 Glucose A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement. Dextrose,Anhydrous Dextrose,D-Glucose,Glucose Monohydrate,Glucose, (DL)-Isomer,Glucose, (alpha-D)-Isomer,Glucose, (beta-D)-Isomer,D Glucose,Dextrose, Anhydrous,Monohydrate, Glucose
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000380 Agranulocytosis A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS). Granulocytopenia,Agranulocytoses,Granulocytopenias

Related Publications

D L Stevens, and E D Everett, and L A Boxer, and R A Landefeld
January 1994, Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg,
D L Stevens, and E D Everett, and L A Boxer, and R A Landefeld
August 1979, The Western journal of medicine,
D L Stevens, and E D Everett, and L A Boxer, and R A Landefeld
November 1984, Journal of the Mississippi State Medical Association,
D L Stevens, and E D Everett, and L A Boxer, and R A Landefeld
January 1984, The American journal of medicine,
D L Stevens, and E D Everett, and L A Boxer, and R A Landefeld
March 1973, The New England journal of medicine,
D L Stevens, and E D Everett, and L A Boxer, and R A Landefeld
March 1986, Medicina clinica,
D L Stevens, and E D Everett, and L A Boxer, and R A Landefeld
January 1969, Acta clinica Belgica,
D L Stevens, and E D Everett, and L A Boxer, and R A Landefeld
July 1986, British journal of haematology,
D L Stevens, and E D Everett, and L A Boxer, and R A Landefeld
January 1986, Henry Ford Hospital medical journal,
D L Stevens, and E D Everett, and L A Boxer, and R A Landefeld
March 2010, International journal of hematology,
Copied contents to your clipboard!