Biomaterial Database

Epicranial plexiform neurofibroma. 1979

J García-Uría, and R G Sola, and R Carrillo, and G Bravo

Epicranial plexiform neurofibroma is a rare presentation of neurofibromatosis. Two such cases are presented in which epicranial tumors constituted isolated manifestations of the disease except for skin pigmentation. Tumor development began at two and three months of age respectively; one case showed a calvarian bony defect associated with the tumor.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009455	Neurofibroma	A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)	Neurofibromas
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012535	Scalp	The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).	Scalps
D012878	Skin Neoplasms	Tumors or cancer of the SKIN.	Cancer of Skin,Skin Cancer,Cancer of the Skin,Neoplasms, Skin,Cancer, Skin,Cancers, Skin,Neoplasm, Skin,Skin Cancers,Skin Neoplasm
D012888	Skull Neoplasms	Neoplasms of the bony part of the skull.	Neoplasms, Skull,Neoplasm, Skull,Skull Neoplasm