Incomplete transformation of plasma fibrinogen to fibrin. Fibrinogen content and streptokinase-induced intra-clot lysis susceptibility of des-AA or des-AABB fibrin clots formed at varying fibrinogen/fibrin ratios.
1979
F Brosstad, and
H C Godal
UI
MeSH Term
Description
Entries
D001777
Blood Coagulation
The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot.
A protein derived from FIBRINOGEN in the presence of THROMBIN, which forms part of the blood clot.
Antithrombin I
D005340
Fibrinogen
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
Coagulation Factor I,Factor I,Blood Coagulation Factor I,gamma-Fibrinogen,Factor I, Coagulation,gamma Fibrinogen
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013300
Streptokinase
Streptococcal fibrinolysin . An enzyme produced by hemolytic streptococci. It hydrolyzes amide linkages and serves as an activator of plasminogen. It is used in thrombolytic therapy and is used also in mixtures with streptodornase (STREPTODORNASE AND STREPTOKINASE). EC 3.4.-.