BIOMAT Database Logo BIOMAT Database Logo

Preparation of 4-(p-(bis(2-chloroethyl)amino)phenyl)butyramides as potential antitumor agents. I. 1974

J H Billman, and G R Roehrig

UI MeSH Term Description Entries
D007939 Leukemia L1210 An experimental LYMPHOCYTIC LEUKEMIA of mice. Leukemia L 1210,L 1210, Leukemia,L1210, Leukemia
D007942 Leukemia, Experimental Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues. Experimental Leukemia,Experimental Leukemias,Leukemia Model, Animal,Leukemias, Experimental,Animal Leukemia Model,Animal Leukemia Models,Leukemia Models, Animal
D009062 Mouth Neoplasms Tumors or cancer of the MOUTH. Cancer of Mouth,Mouth Cancer,Oral Cancer,Oral Neoplasms,Cancer of the Mouth,Neoplasms, Mouth,Neoplasms, Oral,Cancer, Mouth,Cancer, Oral,Cancers, Mouth,Cancers, Oral,Mouth Cancers,Mouth Neoplasm,Neoplasm, Mouth,Neoplasm, Oral,Oral Cancers,Oral Neoplasm
D009588 Nitrogen Mustard Compounds A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens. Compounds, Nitrogen Mustard,Mustard Compounds, Nitrogen
D002087 Butyrates Derivatives of BUTYRIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxypropane structure. Butyrate,n-Butyrate,Butanoic Acids,Butyric Acids,Acids, Butanoic,Acids, Butyric,n Butyrate
D002277 Carcinoma A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for "cancer." Carcinoma, Anaplastic,Carcinoma, Spindle-Cell,Carcinoma, Undifferentiated,Carcinomatosis,Epithelial Neoplasms, Malignant,Epithelioma,Epithelial Tumors, Malignant,Malignant Epithelial Neoplasms,Neoplasms, Malignant Epithelial,Anaplastic Carcinoma,Anaplastic Carcinomas,Carcinoma, Spindle Cell,Carcinomas,Carcinomatoses,Epithelial Neoplasm, Malignant,Epithelial Tumor, Malignant,Epitheliomas,Malignant Epithelial Neoplasm,Malignant Epithelial Tumor,Malignant Epithelial Tumors,Neoplasm, Malignant Epithelial,Spindle-Cell Carcinoma,Spindle-Cell Carcinomas,Tumor, Malignant Epithelial,Undifferentiated Carcinoma,Undifferentiated Carcinomas
D002279 Carcinoma 256, Walker A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed) Carcinosarcoma 256, Walker,Walker Carcinoma 256,Walker Carcinosarcoma 256
D002460 Cell Line Established cell cultures that have the potential to propagate indefinitely. Cell Lines,Line, Cell,Lines, Cell
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000577 Amides Organic compounds containing the -CO-NH2 radical. Amides are derived from acids by replacement of -OH by -NH2 or from ammonia by the replacement of H by an acyl group. (From Grant & Hackh's Chemical Dictionary, 5th ed) Amide

Related Publications

J H Billman, and G R Roehrig
Antitumor activity of homo-aza-steroidal esters of [p-[bis(2-chloroethyl)amino]phenyl]acetic acid and [p-[bis(2-chloroethyl)amino]phenyl]butyric acid.
January 1983, Cancer chemotherapy and pharmacology,
J H Billman, and G R Roehrig
HEXAHYDROPYRIMIDINES. IV. SYNTHESIS OF 2-(4-(N,N-BIS(2-CHLOROETHYL)AMINO)ARYL)-1,3-BIS(ARALKYL)HEXAHYDROPYRIMIDINES AS ANTITUMOR AGENTS.
January 1964, Journal of medicinal chemistry,
J H Billman, and G R Roehrig
Potential antitumor agent dicyclohexylammonium 2-(4-N,N-bis(2-chloroethyl) amino)phenoxy)-2-methylpropionate.
April 1972, Journal of medicinal chemistry,
J H Billman, and G R Roehrig
17-beta-(4'-(p-[bis(beta-chloroethyl)amino]phenyl)-butanoyloxy)-4-androsten-3-one.
September 1968, Journal of medicinal chemistry,
J H Billman, and G R Roehrig
Synthesis and evaluation of esters of N,N-bis(2-chloroethyl)-p-aminophenol and N,N-bis(2-bromoethyl)-p-aminophenol as potential antitumor agents.
May 1969, Journal of medicinal chemistry,
J H Billman, and G R Roehrig
Antitumor and toxicologic effects of p-carboxycarbanilic acid, N-(p-(bis(2-chloroethyl)amino)phenyl) ester (NSC-130998; IC 140).
February 1970, Cancer chemotherapy reports,
J H Billman, and G R Roehrig
New compounds: antitumor activity of 3beta-hydroxy-13alpha-amino-13,17-seco-5alpha-androstan-17-oic-13,17-lactam 4-[p-[bis(2-chloroethyl)amino]phenyl]butyrate.
September 1978, Journal of pharmaceutical sciences,
J H Billman, and G R Roehrig
Antitumor activity of a homo-aza-steroidal ester of (p-(bis(2-chloroethyl)amino)phenyl)acetic acid (NSC-71964).
January 1973, Cancer chemotherapy reports,
J H Billman, and G R Roehrig
Antitumor effects of 3-[p-(N,N-bis-(2'-chloroethyl)amino)-phenyl]-L- alanine conjugated with human immunoglobulin (K18).
January 1990, In vivo (Athens, Greece),
J H Billman, and G R Roehrig
Synthesis of potential antineoplastic agents. 13. 1-p-[Bis(2-chloroethyl)amino] benzyl -pyridinium p-toulenesulfonate and related compounds.
May 1966, Journal of medicinal chemistry,
Copied contents to your clipboard!