-transparent.png){kind=logo}
1 Fluphenazine (1,2-ethanol 14C) was administered to seven human subjects as the dihydrochloride and as the enanthate and decanoate esters. 2 The subjects had previously been treated with fluphenazine injections for at least 6 months. 3 Fluphenazine was separated from its radioactive metabolites by selective solvent extraction. Plasma concentrations were measured for up to 21 days after dosing. 4 The preparations showed differences in peak concentrations, times of the peaks and half-times of the elimination phase. The longest half-times occurred with the decanoate and the shortest with the dihydrochloride. 5 It is postulated that the differences in kinetics relate principally to the release of the compound from the site of injection. 6 There was no evidence for presence of the esters in plasma, urine or faeces.
S H Curry, and
R Whelpton, and
P J de Schepper, and
S Vranckx, and
A A Schiff
February 1979,
Lancet (London, England),
S H Curry, and
R Whelpton, and
P J de Schepper, and
S Vranckx, and
A A Schiff
January 2005,
The Cochrane database of systematic reviews,
S H Curry, and
R Whelpton, and
P J de Schepper, and
S Vranckx, and
A A Schiff
February 2015,
The Cochrane database of systematic reviews,
S H Curry, and
R Whelpton, and
P J de Schepper, and
S Vranckx, and
A A Schiff
January 1968,
Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression,
S H Curry, and
R Whelpton, and
P J de Schepper, and
S Vranckx, and
A A Schiff
December 1990,
Journal of clinical psychopharmacology,
S H Curry, and
R Whelpton, and
P J de Schepper, and
S Vranckx, and
A A Schiff
January 1969,
Psychosomatics,
S H Curry, and
R Whelpton, and
P J de Schepper, and
S Vranckx, and
A A Schiff
January 1975,
Comprehensive psychiatry,
S H Curry, and
R Whelpton, and
P J de Schepper, and
S Vranckx, and
A A Schiff
January 1978,
Neuropsychobiology,
S H Curry, and
R Whelpton, and
P J de Schepper, and
S Vranckx, and
A A Schiff
January 1982,
Pharmacology,
S H Curry, and
R Whelpton, and
P J de Schepper, and
S Vranckx, and
A A Schiff
January 1966,
Psychopharmacologia,
