Biomaterial Database

Cancer of the nasal cavity and ethmoid/sphenoid sinuses. 1979

K E Ellingwood, and R R Million

During the period from October 1964 to September 1975, 32 patients were treated at the University of Florida for a variety of malignant tumors of the nasal cavity and ethmoid/sphenoid sinuses. All were treated with radical irradiation, 6091 to 7972 rad, in 6 to 9 weeks, cobalt-60. Pretreatment work-up revealed evidence of orbital invasion in 7 patients and involvement of the cranial contents, base of skull, or nasopharynx in an additional 15 patients. Local control was achieved in 95% of nasal cavity cases and 71% of ethmoid/sphenoid sinus cases at 2 years or more. The 5-year actuarial survival rate was 59%, and 5-year survival without evidence of disease was 50% (13/26). Patterns of extension in advanced lesions are clues to potential undetected extension in early cases which must be included in the treatment volume. Eye complications were minimal when it was possible to avoid treatment of the entire eye, but developed in all cases requiring treatment of the entire orbit. Acute and chronic complications involving the eye, ear, central nervous system, sinuses, and nose were reviewed and correlated with initial tumor extent, dose, and radiation treatment technique.

UI	MeSH Term	Description	Entries
D008207	Lymphatic Metastasis	Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system.	Lymph Node Metastasis,Lymph Node Metastases,Lymphatic Metastases,Metastasis, Lymph Node
D009296	Nasal Cavity	The proximal portion of the respiratory passages on either side of the NASAL SEPTUM. Nasal cavities, extending from the nares to the NASOPHARYNX, are lined with ciliated NASAL MUCOSA.	Nasal Cavities,Cavities, Nasal,Cavity, Nasal
D009362	Neoplasm Metastasis	The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.	Metastase,Metastasis,Metastases, Neoplasm,Metastasis, Neoplasm,Neoplasm Metastases,Metastases
D009367	Neoplasm Staging	Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.	Cancer Staging,Staging, Neoplasm,Tumor Staging,TNM Classification,TNM Staging,TNM Staging System,Classification, TNM,Classifications, TNM,Staging System, TNM,Staging Systems, TNM,Staging, Cancer,Staging, TNM,Staging, Tumor,System, TNM Staging,Systems, TNM Staging,TNM Classifications,TNM Staging Systems
D009669	Nose Neoplasms	Tumors or cancer of the NOSE.	Cancer of Nose,Nasal Neoplasms,Nose Cancer,Cancer of the Nose,Nasal Cancer,Neoplasms, Nose,Cancer, Nasal,Cancer, Nose,Cancers, Nasal,Cancers, Nose,Nasal Cancers,Nasal Neoplasm,Neoplasm, Nasal,Neoplasm, Nose,Neoplasms, Nasal,Nose Cancers,Nose Neoplasm
D010255	Paranasal Sinus Neoplasms	Tumors or cancer of the PARANASAL SINUSES.	Cancer of Paranasal Sinus,Neoplasms, Paranasal Sinus,Paranasal Sinus Cancer,Cancer, Paranasal Sinus,Cancers, Paranasal Sinus,Neoplasm, Paranasal Sinus,Paranasal Sinus Cancers,Paranasal Sinus Neoplasm
D001766	Blindness	The inability to see or the loss or absence of perception of visual stimuli. This condition may be the result of EYE DISEASES; OPTIC NERVE DISEASES; OPTIC CHIASM diseases; or BRAIN DISEASES affecting the VISUAL PATHWAYS or OCCIPITAL LOBE.	Amaurosis,Bilateral Blindness,Blindness, Bilateral,Blindness, Legal,Blindness, Monocular,Blindness, Unilateral,Sudden Visual Loss,Unilateral Blindness,Blindness, Acquired,Blindness, Complete,Blindness, Hysterical,Blindness, Transient,Acquired Blindness,Amauroses,Bilateral Blindnesses,Complete Blindness,Hysterical Blindness,Legal Blindness,Monocular Blindness,Sudden Visual Losses,Transient Blindness,Visual Loss, Sudden
D001847	Bone Diseases	Diseases of BONES.	Bone Disease,Disease, Bone,Diseases, Bone
D001927	Brain Diseases	Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.	Intracranial Central Nervous System Disorders,Brain Disorders,CNS Disorders, Intracranial,Central Nervous System Disorders, Intracranial,Central Nervous System Intracranial Disorders,Encephalon Diseases,Encephalopathy,Intracranial CNS Disorders,Brain Disease,Brain Disorder,CNS Disorder, Intracranial,Encephalon Disease,Encephalopathies,Intracranial CNS Disorder
D005005	Ethmoid Sinus	The numerous (6-12) small thin-walled spaces or air cells in the ETHMOID BONE located between the eyes. These air cells form an ethmoidal labyrinth.	Bulla Ethmoidalis,Ethmoid Bulla,Ethmoid Sinuses,Ethmoidal Air Cells,Haller Cell,Infraorbital Ethmoid Cell,Onodi Air Cell,Sphenoethmoidal Air Cell,Air Cell, Ethmoidal,Air Cell, Onodi,Bulla Ethmoidali,Bulla, Ethmoid,Cell, Ethmoidal Air,Cell, Haller,Cell, Infraorbital Ethmoid,Cell, Sphenoethmoidal Air,Ethmoid Cell, Infraorbital,Ethmoid Sinuse,Ethmoidal Air Cell,Infraorbital Ethmoid Cells,Sinus, Ethmoid,Sphenoethmoidal Air Cells