An evaluation of the Beckman Creatinine Analyzer 2 has been carried out. Good day-to-day and within-day precision was obtained. Analyses of quality control materials, studies of linearity, and comparison of the results obtained for samples from patients with the results obtained by a continuous-flow method evidenced good accuracy. Aceto-acetate in serum caused significant positive interference. The desirable performance characteristics and practicability make this Analyzer attractive to the clinical chemist, particularly for paediatric and emergency laboratory use.