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The influence of primidone on thyroxine level, T3 index, FT4 index, triiodothyronine level, T3 (RIA)/T4 (RIA) quotient as well as on the TSH basal and stimulated values was investigated in 30 children on long-term treatment. The values obtained were compared statistically with those of a normal group. During primidone treatment a drop in T4 level and in FT4 index as well as an increase in T3 (RIA)/T4 (RIA) quotient was observed. On the other hand the triiodothyronine level and the T3 index were not influenced. The TSH basal and stimulated values were not statistically different from the control group. Thus the primidone-treated children are euthyroid according to the TRH test. Primidone probably stimulates hepatocellular thyroxine breakdown.
W Schönberger, and
W Grimm, and
G Schönberger, and
K Sinterhauf, and
E Scheidt, and
R Ziegler
September 1977,
Nihon Naibunpi Gakkai zasshi,
W Schönberger, and
W Grimm, and
G Schönberger, and
K Sinterhauf, and
E Scheidt, and
R Ziegler
March 1973,
Revista espanola de fisiologia,
W Schönberger, and
W Grimm, and
G Schönberger, and
K Sinterhauf, and
E Scheidt, and
R Ziegler
October 1979,
Rinsho byori. The Japanese journal of clinical pathology,
W Schönberger, and
W Grimm, and
G Schönberger, and
K Sinterhauf, and
E Scheidt, and
R Ziegler
March 1974,
Rinsho byori. The Japanese journal of clinical pathology,
W Schönberger, and
W Grimm, and
G Schönberger, and
K Sinterhauf, and
E Scheidt, and
R Ziegler
July 1981,
Revista medica de Chile,
W Schönberger, and
W Grimm, and
G Schönberger, and
K Sinterhauf, and
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R Ziegler
January 1980,
Annales d'endocrinologie,
W Schönberger, and
W Grimm, and
G Schönberger, and
K Sinterhauf, and
E Scheidt, and
R Ziegler
August 1977,
Monatsschrift fur Kinderheilkunde,
W Schönberger, and
W Grimm, and
G Schönberger, and
K Sinterhauf, and
E Scheidt, and
R Ziegler
May 1977,
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine,
W Schönberger, and
W Grimm, and
G Schönberger, and
K Sinterhauf, and
E Scheidt, and
R Ziegler
April 1974,
Zeitschrift fur Geburtshilfe und Perinatologie,
W Schönberger, and
W Grimm, and
G Schönberger, and
K Sinterhauf, and
E Scheidt, and
R Ziegler
August 1974,
Rinsho byori. The Japanese journal of clinical pathology,
