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Isolation of a neurosecretory substance which stimulates RNA synthesis in regenerating planarians. 1979

R A Webb, and T Friedel

An approach to the isolation of neurosecretory material from planarians is described. This material stimulated RNA synthesis, in a dose-dependent response, in regenerating Dugesia tigrina. The data support the concept that neurosecretion plays a key role in the process of regeneration in planarians.

UI MeSH Term Description Entries
D009489 Neurosecretion The production and release of substances such as NEUROTRANSMITTERS or HORMONES from nerve cells. Neurosecretions
D010932 Planarians Nonparasitic free-living flatworms of the class Turbellaria. The most common genera are Dugesia, formerly Planaria, which lives in water, and Bipalium, which lives on land. Geoplana occurs in South America and California. Dugesia,Dugesias,Planarian
D012038 Regeneration The physiological renewal, repair, or replacement of tissue. Endogenous Regeneration,Regeneration, Endogenous,Regenerations
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012313 RNA A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed) RNA, Non-Polyadenylated,Ribonucleic Acid,Gene Products, RNA,Non-Polyadenylated RNA,Acid, Ribonucleic,Non Polyadenylated RNA,RNA Gene Products,RNA, Non Polyadenylated
D014419 Turbellaria A class of free-living freshwater flatworms of North America. Turbellarias
D014529 Uridine A ribonucleoside in which RIBOSE is linked to URACIL. Allo-Uridine,Allouridine,Allo Uridine

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