Biomaterial Database

The dynamics of contraction in the guinea pig taenia coli. 1979

H Mashima, and T Okada, and H Okuyama

Tension-length, load-velocity and tension-extension relations were studied in the taenia coli muscle of the guinea pig weighing 0.25--0.5 kg at 36--37 degrees C. The muscle was relaxed by 10(-6) g/ml adrenaline and stimulated by a strong AC field. The tension-length diagram was far wider than that of the skeletal muscle and sufficient tension was generated at longer lengths than 1.8 Lm, where Lm is the optimal length at which the maximum tension, Fm, is generated. The developed force per unit cross-sectional area was almost unchanged between 1.2--2.0 Lm. Average of the maximum forces was 2.2 kg/cm2. Load-velocity curves obtained at various isometric forces at Lm coincided with each other, if the velocity was plotted against the relative force. All curves can be expressed by a single force-load-velocity equation, (P+A)(v+b)=b(F+A), A=(F/Fm)a, where P is the load, F the isometric force, v the velocity, a and b are constants. The maximum velocity per unit muscle length was constant, irrespective of the muscle length. The compliance of the series elastic component, that is, the slope of the tension-extension curve, did not depend on the isometric force but decreased with decreasing muscle length. The internal lengthening of the series elastic component by the full isometric tension was about 3% of the muscle length at Lm.

UI	MeSH Term	Description	Entries
D008954	Models, Biological	Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.	Biological Model,Biological Models,Model, Biological,Models, Biologic,Biologic Model,Biologic Models,Model, Biologic
D009119	Muscle Contraction	A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.	Inotropism,Muscular Contraction,Contraction, Muscle,Contraction, Muscular,Contractions, Muscle,Contractions, Muscular,Inotropisms,Muscle Contractions,Muscular Contractions
D009130	Muscle, Smooth	Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)	Muscle, Involuntary,Smooth Muscle,Involuntary Muscle,Involuntary Muscles,Muscles, Involuntary,Muscles, Smooth,Smooth Muscles
D003106	Colon	The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.	Appendix Epiploica,Taenia Coli,Omental Appendices,Omental Appendix,Appendices, Omental,Appendix, Omental
D004548	Elasticity	Resistance and recovery from distortion of shape.
D006168	Guinea Pigs	A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.	Cavia,Cavia porcellus,Guinea Pig,Pig, Guinea,Pigs, Guinea
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D066298	In Vitro Techniques	Methods to study reactions or processes taking place in an artificial environment outside the living organism.	In Vitro Test,In Vitro Testing,In Vitro Tests,In Vitro as Topic,In Vitro,In Vitro Technique,In Vitro Testings,Technique, In Vitro,Techniques, In Vitro,Test, In Vitro,Testing, In Vitro,Testings, In Vitro,Tests, In Vitro,Vitro Testing, In