Magnetic resonance studies on membrane and model membrane system: proton magnetic relaxation rates in sonicated lecithin dispersions. 1972

A F Horwitz, and W J Horsley, and M P Klein

We have used Fourier transform nuclear magnetic resonance methods to measure the spin-lattice and transverse relaxation times at 220 MHz of the choline N-methyl and the fatty-acid alpha-carbonyl, allyl, vinyl, methylene, and methyl protons of sonicated egg-yolk lecithin. Over the temperature range investigated the T(1) values were, in general, similar to, but different from, one another, suggesting that the relaxation rates of all of the fatty-acid protons are not determined solely by spin-diffusion to a heat sink. Arrhenius plots of the T(1) data gave activation energies similar to those for the barriers to internal rotation in alkanes. The values of the transverse relaxation rate, T(2), showed a relatively large variation among the proton resonances; about 20% of the methylene protons had a T(2) of 56 msec, while the remaining protons relaxed according to a distribution of values all shorter than 20 msec. Such a distribution of relaxation times is envisioned to arise from a distribution of correlation times stemming from complex motions in which extended angular excursions of the fatty acid chain are coupled to trans-->gauche conformational transitions.

UI MeSH Term Description Entries
D009682 Magnetic Resonance Spectroscopy Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING). In Vivo NMR Spectroscopy,MR Spectroscopy,Magnetic Resonance,NMR Spectroscopy,NMR Spectroscopy, In Vivo,Nuclear Magnetic Resonance,Spectroscopy, Magnetic Resonance,Spectroscopy, NMR,Spectroscopy, Nuclear Magnetic Resonance,Magnetic Resonance Spectroscopies,Magnetic Resonance, Nuclear,NMR Spectroscopies,Resonance Spectroscopy, Magnetic,Resonance, Magnetic,Resonance, Nuclear Magnetic,Spectroscopies, NMR,Spectroscopy, MR
D010713 Phosphatidylcholines Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety. Choline Phosphoglycerides,Choline Glycerophospholipids,Phosphatidyl Choline,Phosphatidyl Cholines,Phosphatidylcholine,Choline, Phosphatidyl,Cholines, Phosphatidyl,Glycerophospholipids, Choline,Phosphoglycerides, Choline
D011522 Protons Stable elementary particles having the smallest known positive charge, found in the nuclei of all elements. The proton mass is less than that of a neutron. A proton is the nucleus of the light hydrogen atom, i.e., the hydrogen ion. Hydrogen Ions,Hydrogen Ion,Ion, Hydrogen,Ions, Hydrogen,Proton
D004530 Egg Yolk Cytoplasm stored in an egg that contains nutritional reserves for the developing embryo. It is rich in polysaccharides, lipids, and proteins. Egg Yolks,Yolk, Egg,Yolks, Egg
D005260 Female Females

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