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A 29-year-old woman sustained an acute massive pulmonary embolism in the 32nd week of pregnancy. Rapid clinical improvement followed the use of streptokinase. Treatment was continued for 41 hours, including labour and the first three hours after delivery. There was slow but severe postpartum haemorrhage. Partial uterine atony occurred, and may have been due, at least in part, to fibrin degradation products arising from thrombolysis. No adverse effects were noted in the baby.Our experience suggests that streptokinase may be given during labour but that an oxytocic agent may be needed; and that reversal of fibrinolysis before delivery is best achieved by the use of aprotinin (Trasylol) rather than aminocaproic acid.
R J Hall, and
C Young, and
G C Sutton, and
S Cambell
January 1977,
The Medical journal of Australia,
R J Hall, and
C Young, and
G C Sutton, and
S Cambell
June 1971,
British medical journal,
R J Hall, and
C Young, and
G C Sutton, and
S Cambell
July 1971,
British heart journal,
R J Hall, and
C Young, and
G C Sutton, and
S Cambell
January 1990,
Acta obstetricia et gynecologica Scandinavica,
R J Hall, and
C Young, and
G C Sutton, and
S Cambell
May 1977,
American heart journal,
R J Hall, and
C Young, and
G C Sutton, and
S Cambell
September 1967,
Lancet (London, England),
R J Hall, and
C Young, and
G C Sutton, and
S Cambell
May 2004,
Kardiologia polska,
R J Hall, and
C Young, and
G C Sutton, and
S Cambell
January 1987,
Respiration; international review of thoracic diseases,
R J Hall, and
C Young, and
G C Sutton, and
S Cambell
October 2020,
Cureus,
R J Hall, and
C Young, and
G C Sutton, and
S Cambell
January 1986,
Folia haematologica (Leipzig, Germany : 1928),
