[The biochemical mechanism of action of carcinogenic N-nitroso compounds].
1972
F W Krüger
UI
MeSH Term
Description
Entries
D007454
Iodides
Inorganic binary compounds of iodine or the I- ion.
Iodide
D007668
Kidney
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
Kidneys
D007928
Lethal Dose 50
The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
LD50,Dose 50, Lethal
D008099
Liver
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
Livers
D008168
Lung
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Lungs
D009336
Necrosis
The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
D009602
Nitrosamines
A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties.
Nitrosamine
D009603
Nitroso Compounds
Organic compounds containing the nitroso (-N
Compounds, Nitroso
D009696
Nucleic Acids
High molecular weight polymers containing a mixture of purine and pyrimidine nucleotides chained together by ribose or deoxyribose linkages.
Nucleic Acid,Acid, Nucleic,Acids, Nucleic
D002273
Carcinogens
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.