Comparative study of the growth inhibition of vegetative hyphae of some dermatophytes and keratinophilic fungi on glucose-peptone-agar with griseofulvin. 1979

Z Jesenská

By the method of Jesenská and Danilla [29] the growth inhibition of vegetative hyphae of colonies of 12 species of dermatophytes and keratinophilic fungi on the surface of glucose-peptone-agar with incorporated griseofulvin has been established. It could be concluded that the sensitivity of hyphae to griseofulvin is neither connected with the taxonomic position and ecological classification of these microscopic fungi, nor with their ability to survive in the soil, or with their pathogenity etc. - In Trichophyton rubrum some hyphae were found which were extremely resistant to griseofulvin. - The extablished values allow to make an objective comparison of the sensitivity level of vegetative hyphae of dermatophytes and keratinophilic fungi to griseofulvin in further geographical regions, at different times and in different laboratories. - In the discussion further possibilities in this direction are developed.

UI MeSH Term Description Entries
D008864 Microsporum A mitosporic Oxygenales fungal genus causing various diseases of the skin and hair. The species Microsporum canis produces TINEA CAPITIS and tinea corporis, which usually are acquired from domestic cats and dogs. Teleomorphs includes Arthroderma (Nannizzia). (Alexopoulos et al., Introductory Mycology, 4th edition, p305) Microsporon,Microsporons,Microsporums
D003470 Culture Media Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN. Media, Culture
D003883 Arthrodermataceae A family of ascomycetous fungi, order Onygenales, characterized by smooth ascospores. Genera in the family include Arthroderma, Keratinomyces, and Ctenomyces. Several well-known anamorphic forms are parasitic upon the skin. Arthroderma,Ctenomyces,Dermatophytes,Keratinomyces,Cutaneous Fungi,Cutaneous Fungus,Dermatomyces,Nannizzia,Arthrodermas,Ctenomyce,Dermatomyce,Dermatophyte,Fungi, Cutaneous,Fungus, Cutaneous,Keratinomyce,Nannizzias
D006118 Griseofulvin An antifungal agent used in the treatment of TINEA infections. Fulvicin-U-F,Grifulvin V,Gris-PEG,Grisactin,Grisefuline,Fulvicin U F,FulvicinUF,Gris PEG,GrisPEG
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