'Human' and 'animal' carcinogens. 1979

B Teichmann, and T Schramm

A clarification is made of the meanings of the terms 'human carcinogen' and 'animal carcinogen' in cancer research, cancer prevention and legislative actions. A chemical proven to have carcinogenic activity in animals should be considered to represent a risk to humans. However, non-experts tend to consider that 'animal carcinogens' produce cancer only in animals and can be neglected with regard to the human situation. The use of these terms should thus be avoided or they should be used as standard terms based on generally accepted and available definitions.

UI MeSH Term Description Entries
D009374 Neoplasms, Experimental Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms. Experimental Neoplasms,Experimental Neoplasm,Neoplasm, Experimental
D002273 Carcinogens Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. Carcinogen,Oncogen,Oncogens,Tumor Initiator,Tumor Initiators,Tumor Promoter,Tumor Promoters,Initiator, Tumor,Initiators, Tumor,Promoter, Tumor,Promoters, Tumor
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000830 Animals, Laboratory Animals used or intended for use in research, testing, or teaching. Laboratory Animals,Animal, Laboratory,Laboratory Animal

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