BIOMAT Database Logo BIOMAT Database Logo

Effect of methionine and vitamin B-12 on the activities of methionine biosynthetic enzymes in metJ mutants of Escherichia coli K12. 1973

R C Greene, and R D Williams, and H F Kung, and C Spears, and H Weissbach

UI MeSH Term Description Entries
D008715 Methionine A sulfur-containing essential L-amino acid that is important in many body functions. L-Methionine,Liquimeth,Methionine, L-Isomer,Pedameth,L-Isomer Methionine,Methionine, L Isomer
D008780 Methyltransferases A subclass of enzymes of the transferase class that catalyze the transfer of a methyl group from one compound to another. (Dorland, 28th ed) EC 2.1.1. Methyltransferase
D009154 Mutation Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations. Mutations
D010088 Oxidoreductases The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. (Enzyme Nomenclature, 1992, p9) Dehydrogenases,Oxidases,Oxidoreductase,Reductases,Dehydrogenase,Oxidase,Reductase
D003470 Culture Media Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN. Media, Culture
D003540 Cystathionine Sulfur-containing amino acid formed as an intermediate in the conversion of METHIONINE to CYSTEINE.
D004794 Enzyme Repression The interference in synthesis of an enzyme due to the elevated level of an effector substance, usually a metabolite, whose presence would cause depression of the gene responsible for enzyme synthesis. Repression, Enzyme
D004926 Escherichia coli A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc. Alkalescens-Dispar Group,Bacillus coli,Bacterium coli,Bacterium coli commune,Diffusely Adherent Escherichia coli,E coli,EAggEC,Enteroaggregative Escherichia coli,Enterococcus coli,Diffusely Adherent E. coli,Enteroaggregative E. coli,Enteroinvasive E. coli,Enteroinvasive Escherichia coli
D005492 Folic Acid A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. Pteroylglutamic Acid,Vitamin M,Folacin,Folate,Folic Acid, (D)-Isomer,Folic Acid, (DL)-Isomer,Folic Acid, Calcium Salt (1:1),Folic Acid, Monopotassium Salt,Folic Acid, Monosodium Salt,Folic Acid, Potassium Salt,Folic Acid, Sodium Salt,Folvite,Vitamin B9,B9, Vitamin
D006710 Homocysteine A thiol-containing amino acid formed by a demethylation of METHIONINE. 2-amino-4-mercaptobutyric acid,Homocysteine, L-Isomer,2 amino 4 mercaptobutyric acid,Homocysteine, L Isomer,L-Isomer Homocysteine

Related Publications

R C Greene, and R D Williams, and H F Kung, and C Spears, and H Weissbach
Effect of L-methionine and vitamin B 12 on methionine biosynthesis in Escherichia coli.
September 1969, Archives of biochemistry and biophysics,
R C Greene, and R D Williams, and H F Kung, and C Spears, and H Weissbach
Overexpression in Escherichia coli of 12 vitamin B12 biosynthetic enzymes.
April 1995, Protein expression and purification,
R C Greene, and R D Williams, and H F Kung, and C Spears, and H Weissbach
Vitamin B 12 and methionine synthesis in Escherichia coli.
June 1971, Biochimica et biophysica acta,
R C Greene, and R D Williams, and H F Kung, and C Spears, and H Weissbach
Cloning of the methionine regulatory gene, metJ, of Escherichia coli K12 and identification of its product.
November 1984, The Journal of biological chemistry,
R C Greene, and R D Williams, and H F Kung, and C Spears, and H Weissbach
Isolation of vitamin B 12 transport mutants of Escherichia coli.
June 1971, Journal of bacteriology,
R C Greene, and R D Williams, and H F Kung, and C Spears, and H Weissbach
Immunological cross reactivity of four enzymes involved in the biosynthetic pathway of lysine, methionine and threonine in Escherichia coli K12.
January 1976, Acta microbiologica Academiae Scientiarum Hungaricae,
R C Greene, and R D Williams, and H F Kung, and C Spears, and H Weissbach
Mechanism of L-methionine overproduction by Escherichia coli: the replacement of Ser-54 by Asn in the MetJ protein causes the derepression of L-methionine biosynthetic enzymes.
August 1999, Applied microbiology and biotechnology,
R C Greene, and R D Williams, and H F Kung, and C Spears, and H Weissbach
[The role of methionine in the metabolism of vitamin B 12- and methionine-dependent Escherichia coli strains].
January 1970, Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite naturwissenschaftliche Abt.: Allgemeine, landwirtschaftliche und technische Mikrobiologie,
R C Greene, and R D Williams, and H F Kung, and C Spears, and H Weissbach
Isolation and characterization of the product of the methionine-regulatory gene metJ of Escherichia coli K-12.
September 1985, Proceedings of the National Academy of Sciences of the United States of America,
R C Greene, and R D Williams, and H F Kung, and C Spears, and H Weissbach
Regulation of methionine biosynthesis in Escherichia coli: mapping of the metJ locus and properties of a metJ plus-metJ minus diploid.
February 1971, Proceedings of the National Academy of Sciences of the United States of America,
Copied contents to your clipboard!