Biomaterial Database

Statistical considerations for dominant lethal mutagenic trials. 1973

D S Salsburg

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009154	Mutation	Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.	Mutations
D010064	Embryo Implantation	Endometrial implantation of EMBRYO, MAMMALIAN at the BLASTOCYST stage.	Blastocyst Implantation,Decidual Cell Reaction,Implantation, Blastocyst,Nidation,Ovum Implantation,Blastocyst Implantations,Decidual Cell Reactions,Embryo Implantations,Implantation, Embryo,Implantation, Ovum,Implantations, Blastocyst,Implantations, Embryo,Implantations, Ovum,Nidations,Ovum Implantations
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D011336	Probability	The study of chance processes or the relative frequency characterizing a chance process.	Probabilities
D003201	Computers	Programmable electronic devices designed to accept data, perform prescribed mathematical and logical operations at high speed, and display the results of these operations.	Calculators, Programmable,Computer Hardware,Computers, Digital,Hardware, Computer,Calculator, Programmable,Computer,Computer, Digital,Digital Computer,Digital Computers,Programmable Calculator,Programmable Calculators
D004345	Drug Industry	That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.	Industries, Pharmaceutic,Industry, Drug,Industry, Pharmaceutic,Industry, Pharmaceutical,Pharmaceutical Industry,Drug Industries,Industries, Drug,Industries, Pharmaceutical,Pharmaceutic Industries,Pharmaceutic Industry,Pharmaceutical Industries
D005260	Female		Females
D005313	Fetal Death	Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.	Fetal Mummification,Fetal Demise,Death, Fetal,Deaths, Fetal,Demise, Fetal,Fetal Deaths,Mummification, Fetal
D005799	Genes, Dominant	Genes that influence the PHENOTYPE both in the homozygous and the heterozygous state.	Conditions, Dominant Genetic,Dominant Genetic Conditions,Genetic Conditions, Dominant,Condition, Dominant Genetic,Dominant Gene,Dominant Genes,Dominant Genetic Condition,Gene, Dominant,Genetic Condition, Dominant

Related Publications

D S Salsburg

The dominant-lethal test: potential limitations and statistical considerations for safety evaluation.

December 1973, Environmental health perspectives,

D S Salsburg

Antifertility effects and dominant lethal assays for mutagenic effects of DEHP.

November 1982, Environmental health perspectives,

D S Salsburg

Dominant lethal test in the mouse for mutagenic effects of saccharine.

July 1973, Humangenetik,

D S Salsburg

Mutagenic potential of cypermethrin in mouse dominant lethal assay.

January 2002, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer,

D S Salsburg

Mutagenic evaluation of deltamethrin using rodent dominant lethal assay.

May 2000, Mutation research,

D S Salsburg

Basket Designs: Statistical Considerations for Oncology Trials.

December 2019, JCO precision oncology,

D S Salsburg

Statistical considerations in clinical trials.

January 1990, Muscle & nerve,

D S Salsburg

Use of the beta-binomial distribution in dominant-lethal testing for "weak mutagenic activity".

September 1977, Mutation research,