BIOMAT Database Logo BIOMAT Database Logo

C-peptide immunoreactivity (CPR): a new method for studying infants of insulin-treated diabetic mothers. 1974

M B Block, and R S Pildes, and N A Mossabhoy, and D F Steiner, and A H Rubenstein

UI MeSH Term Description Entries
D007118 Immunoassay A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance. Immunochromatographic Assay,Assay, Immunochromatographic,Assays, Immunochromatographic,Immunoassays,Immunochromatographic Assays
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007328 Insulin A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). Iletin,Insulin A Chain,Insulin B Chain,Insulin, Regular,Novolin,Sodium Insulin,Soluble Insulin,Chain, Insulin B,Insulin, Sodium,Insulin, Soluble,Regular Insulin
D007515 Islets of Langerhans Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN. Islands of Langerhans,Islet Cells,Nesidioblasts,Pancreas, Endocrine,Pancreatic Islets,Cell, Islet,Cells, Islet,Endocrine Pancreas,Islet Cell,Islet, Pancreatic,Islets, Pancreatic,Langerhans Islands,Langerhans Islets,Nesidioblast,Pancreatic Islet
D008431 Maternal-Fetal Exchange Exchange of substances between the maternal blood and the fetal blood at the PLACENTA via PLACENTAL CIRCULATION. The placental barrier excludes microbial or viral transmission. Transplacental Exposure,Exchange, Maternal-Fetal,Exposure, Transplacental,Maternal Fetal Exchange
D010455 Peptides Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are considered to be larger versions of peptides that can form into complex structures such as ENZYMES and RECEPTORS. Peptide,Polypeptide,Polypeptides
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011254 Pregnancy in Diabetics The state of PREGNANCY in women with DIABETES MELLITUS. This does not include either symptomatic diabetes or GLUCOSE INTOLERANCE induced by pregnancy (DIABETES, GESTATIONAL) which resolves at the end of pregnancy. Pregnancy in Diabetes,Pregnancy in Diabete,Pregnancy in Diabetic
D011384 Proinsulin A pancreatic polypeptide of about 110 amino acids, depending on the species, that is the precursor of insulin. Proinsulin, produced by the PANCREATIC BETA CELLS, is comprised sequentially of the N-terminal B-chain, the proteolytically removable connecting C-peptide, and the C-terminal A-chain. It also contains three disulfide bonds, two between A-chain and B-chain. After cleavage at two locations, insulin and C-peptide are the secreted products. Intact proinsulin with low bioactivity also is secreted in small amounts.
D002850 Chromatography, Gel Chromatography on non-ionic gels without regard to the mechanism of solute discrimination. Chromatography, Exclusion,Chromatography, Gel Permeation,Chromatography, Molecular Sieve,Gel Filtration,Gel Filtration Chromatography,Chromatography, Size Exclusion,Exclusion Chromatography,Gel Chromatography,Gel Permeation Chromatography,Molecular Sieve Chromatography,Chromatography, Gel Filtration,Exclusion Chromatography, Size,Filtration Chromatography, Gel,Filtration, Gel,Sieve Chromatography, Molecular,Size Exclusion Chromatography

Related Publications

M B Block, and R S Pildes, and N A Mossabhoy, and D F Steiner, and A H Rubenstein
C-peptide immunoreactivity (CPR) in urine.
January 1978, Diabetes,
M B Block, and R S Pildes, and N A Mossabhoy, and D F Steiner, and A H Rubenstein
Free C-peptide immunoreactivity in insulin-treated diabetics.
April 1977, Endocrinologia japonica,
M B Block, and R S Pildes, and N A Mossabhoy, and D F Steiner, and A H Rubenstein
[New index for the diagnosis of insulinoma--serum C-peptide immunoreactivity (CPR) and CPR/blood sugar ratio].
April 1977, Horumon to rinsho. Clinical endocrinology,
M B Block, and R S Pildes, and N A Mossabhoy, and D F Steiner, and A H Rubenstein
Amniotic fluid insulin, C peptide concentrations, and fetal morbidity in infants of diabetic mothers.
November 1985, American journal of obstetrics and gynecology,
M B Block, and R S Pildes, and N A Mossabhoy, and D F Steiner, and A H Rubenstein
[C-peptide immunoreactivity CPR), urine CPR, beta-cell function (author's transl)].
June 1981, Nihon Ika Daigaku zasshi,
M B Block, and R S Pildes, and N A Mossabhoy, and D F Steiner, and A H Rubenstein
Circadian variation of serum glucose, C-peptide immunoreactivity and free insulin normal and insulin-treated diabetic pregnant subjects.
August 1976, Diabetologia,
M B Block, and R S Pildes, and N A Mossabhoy, and D F Steiner, and A H Rubenstein
Sequential changes in beta-cell function in insulin-treated diabetic patients assessed by C-peptide immunoreactivity.
May 1973, The New England journal of medicine,
M B Block, and R S Pildes, and N A Mossabhoy, and D F Steiner, and A H Rubenstein
Hormonal enteroinsular axis in newborn infants of insulin-treated diabetic mothers.
November 1993, The Journal of clinical endocrinology and metabolism,
M B Block, and R S Pildes, and N A Mossabhoy, and D F Steiner, and A H Rubenstein
[Macrosomatia in newborn infants of diabetic mothers treated with insulin (case studies)].
May 1977, Minerva pediatrica,
M B Block, and R S Pildes, and N A Mossabhoy, and D F Steiner, and A H Rubenstein
Determination of total insulin (TIRI) in plasma of insulin-treated diabetics and newborn infants of insulin-treated diabetic mothers.
December 1975, Endokrinologie,
Copied contents to your clipboard!