-transparent.png){kind=logo}
Twenty-one cases of beta 0 and beta +-thalassaemia have been analysed by restriction endonuclease mapping. In most cases no deletion in the regions surrounding the beta- and delta-globin genes could be detected. However, in a single Asian case of beta 0-thalassaemia, homozygous clinically, one of the homologous chromosomes contained a beta-globin gene with a deletion of 600 base pairs of DNA and comprising most or all of the 3' end of the structural gene including the EcoRI restriction site within the beta-globin coding sequence.
Related Publications
R A Flavell, and
R Bernards, and
J M Kooter, and
E de Boer, and
P F Little, and
G Annison, and
R Williamson
April 1982,
Nature,
R A Flavell, and
R Bernards, and
J M Kooter, and
E de Boer, and
P F Little, and
G Annison, and
R Williamson
May 1997,
British journal of haematology,
R A Flavell, and
R Bernards, and
J M Kooter, and
E de Boer, and
P F Little, and
G Annison, and
R Williamson
July 2006,
British journal of haematology,
R A Flavell, and
R Bernards, and
J M Kooter, and
E de Boer, and
P F Little, and
G Annison, and
R Williamson
January 1983,
Nature,
R A Flavell, and
R Bernards, and
J M Kooter, and
E de Boer, and
P F Little, and
G Annison, and
R Williamson
December 1993,
Nature,
R A Flavell, and
R Bernards, and
J M Kooter, and
E de Boer, and
P F Little, and
G Annison, and
R Williamson
March 2004,
British journal of haematology,
R A Flavell, and
R Bernards, and
J M Kooter, and
E de Boer, and
P F Little, and
G Annison, and
R Williamson
January 1976,
Nature,
R A Flavell, and
R Bernards, and
J M Kooter, and
E de Boer, and
P F Little, and
G Annison, and
R Williamson
May 1987,
British journal of haematology,
R A Flavell, and
R Bernards, and
J M Kooter, and
E de Boer, and
P F Little, and
G Annison, and
R Williamson
April 1991,
Journal of medical genetics,
R A Flavell, and
R Bernards, and
J M Kooter, and
E de Boer, and
P F Little, and
G Annison, and
R Williamson
March 1987,
British journal of haematology,
