Biomaterial Database

Functional residual capacity during anaesthesia. II. Spontaneous respiration. 1974

A M Hewlett, and G H Hulands, and J F Nunn, and J R Heath

Functional residual capacity has been measured by helium dilution in 26 spontaneously breathing patients before and immediately after anaesthesia, which was induced with thiopentone and maintained with halothane. The mean reduction was 390 ml (16.1% or pre-induction value) and the change was highly significant (P less than 0.001). The decrease in FRC correlated with age (r equals 0.41: P less than 0.005) and less (P less than 0.001). The decrease in FRC correlated with age (r equals 0.41; P less than 0.005) and less satisfactorily with the weight/height ratio (r equals 0.31; P less than 0.05) which itself correlated with age. Inspired oxygen concentration, expiratory reserve volume and the presence of phasic expiratory muscle activity bore no significant relationship to the decrease in FRC. There was no evidence of any progressive change in FRC between 6 and 20 min after the induction of anaesthesia.

UI	MeSH Term	Description	Entries
D007201	Indicator Dilution Techniques	Methods for assessing flow through a system by injection of a known quantity of an indicator, such as a dye, radionuclide, or chilled liquid, into the system and monitoring its concentration over time at a specific point in the system. (From Dorland, 28th ed)	Dilution Techniques,Dilution Technics,Indicator Dilution Technics,Dilution Technic,Dilution Technic, Indicator,Dilution Technics, Indicator,Dilution Technique,Dilution Technique, Indicator,Dilution Techniques, Indicator,Indicator Dilution Technic,Indicator Dilution Technique,Technic, Dilution,Technic, Indicator Dilution,Technics, Dilution,Technics, Indicator Dilution,Technique, Dilution,Technique, Indicator Dilution,Techniques, Dilution,Techniques, Indicator Dilution
D007366	Intercostal Muscles	Respiratory muscles that arise from the lower border of one rib and insert into the upper border of the adjoining rib, and contract during inspiration or respiration. (From Stedman, 25th ed)	Intercostal Muscle,Muscle, Intercostal,Muscles, Intercostal
D008170	Lung Compliance	The capability of the LUNGS to distend under pressure as measured by pulmonary volume change per unit pressure change. While not a complete description of the pressure-volume properties of the lung, it is nevertheless useful in practice as a measure of the comparative stiffness of the lung. (From Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p562)	Compliance, Lung,Compliances, Lung,Lung Compliances
D008176	Lung Volume Measurements	Measurement of the amount of air that the lungs may contain at various points in the respiratory cycle.	Lung Capacities,Lung Volumes,Capacity, Lung,Lung Capacity,Lung Volume,Lung Volume Measurement,Measurement, Lung Volume,Volume, Lung
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010100	Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.	Dioxygen,Oxygen-16,Oxygen 16
D012115	Residual Volume	The volume of air remaining in the LUNGS at the end of a maximal expiration. Common abbreviation is RV.	Residual Volumes,Volume, Residual,Volumes, Residual
D012119	Respiration	The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (	Breathing
D001827	Body Height	The distance from the sole to the crown of the head with body standing on a flat surface and fully extended.	Body Heights,Height, Body,Heights, Body