-transparent.png){kind=logo}
Human factor VIII has been dissociated into fragment VIII-C and fragment VIII-AG in the presence of calcium chloride (0.25 M). After removing the calcium, recombination of the molecule is obtained. Fragment VIII-C can be activated by thrombin in a similar manner to the coagulant activity of whole factor VIII. This activation is calcium-dependent. In rabbits immunized against purified F VIII, VIII-C and VIII-AG specific antisera against these three entities were obtained.
Related Publications
T H Tran, and
H Bounameaux, and
G A Marbet, and
F Duckert
August 1973,
Proceedings of the National Academy of Sciences of the United States of America,
T H Tran, and
H Bounameaux, and
G A Marbet, and
F Duckert
August 1981,
Thrombosis and haemostasis,
T H Tran, and
H Bounameaux, and
G A Marbet, and
F Duckert
February 1984,
Thrombosis and haemostasis,
T H Tran, and
H Bounameaux, and
G A Marbet, and
F Duckert
March 1977,
Thrombosis research,
T H Tran, and
H Bounameaux, and
G A Marbet, and
F Duckert
October 1981,
European journal of pediatrics,
T H Tran, and
H Bounameaux, and
G A Marbet, and
F Duckert
November 1975,
Thrombosis et diathesis haemorrhagica,
T H Tran, and
H Bounameaux, and
G A Marbet, and
F Duckert
May 1991,
Genomics,
T H Tran, and
H Bounameaux, and
G A Marbet, and
F Duckert
June 1958,
Proceedings of the National Academy of Sciences of the United States of America,
T H Tran, and
H Bounameaux, and
G A Marbet, and
F Duckert
August 1988,
Proceedings of the National Academy of Sciences of the United States of America,
T H Tran, and
H Bounameaux, and
G A Marbet, and
F Duckert
October 1989,
The Biochemical journal,
