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Serum 63 patients with porphyria cutanea tarda (PCT) was examined for the presence of HBs-antigen and anti-HBs by the CombRIA-Au method. HBs-antigen was not detected in any of the examined blood samples. In contrast to these findings in 12 of the 63 PCT-patients (= 28 per cent), anti HBs was detected in the serum. The results showed that a high percentage of our PCT patients had been afflicted with an inapparent hepatitis B and were producing HBs-antibodies.
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