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The palmarfascia of 30 patients with Dupuytrens disease was investigated light- and electron microscopically. As typical changes there exist an increase in cells which form noduli. Many cells contain contractile filaments in their cytoplasma are therefore described as myofibroblasts. Beside these cells active fibroblasts could be observed. Close to their cell membranes there occur filaments with a diameter of 100--300 A. In a greater distance fibrils and fibers with a diameter of 400--600 A were observed. The regular order of the connective tissue is disturbed, one often can observe "vortex" like structures. The lumina of many capillaries are collapsed. The pericytes are increased. The nerve fibers are morphologically unchanged - they are often closely surrounded by collagen fibers. Respecting the morphological findings the pathogenesis of Dupuytrens disease is discussed.
W Noack, and
K R Weingärtner
January 1982,
Anatomischer Anzeiger,
W Noack, and
K R Weingärtner
July 1975,
Virchows Archiv. A, Pathological anatomy and histology,
W Noack, and
K R Weingärtner
January 1974,
Beitrage zur Pathologie,
W Noack, and
K R Weingärtner
January 1971,
Verhandlungen der Deutschen Gesellschaft fur Pathologie,
W Noack, and
K R Weingärtner
January 1976,
Archives d'anatomie et de cytologie pathologiques,
W Noack, and
K R Weingärtner
October 1977,
Archiv fur Gynakologie,
W Noack, and
K R Weingärtner
February 1974,
Zeitschrift fur Orthopadie und ihre Grenzgebiete,
W Noack, and
K R Weingärtner
November 1977,
Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie,
W Noack, and
K R Weingärtner
June 1975,
Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie,
W Noack, and
K R Weingärtner
January 1981,
Annales de pathologie,
