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Reports on the effect of methylergometrine hydrogenmaleate (MEM) on prolactin (PRL) secretion and lactation are still controversial. Therefore a prospective study was designed to follow the influence of MEM on post-partum PRL levels and milk production. MEM was given orally to 30 post-partum women from day 1 to day 7 in a daily dose of 0.6 mg. Thirty untreated women served as control. PRL plasma levels and milk yield were compared at day 1, 3 and 7. PRL levels were significantly lower in the treated group at day 7 (P less than 0.01), while the difference at day 3 was statistically not significant. Milk yield was significantly reduced at day 3 (P less than 0.05) and day 7 (P less than 0.01). These results indicate PRL inhibiting properties of MEM resulting consequently in reduced lactation.
F Peters, and
M Lummerich, and
M Breckwoldt
March 2023,
iScience,
F Peters, and
M Lummerich, and
M Breckwoldt
January 1980,
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F Peters, and
M Lummerich, and
M Breckwoldt
May 1977,
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F Peters, and
M Lummerich, and
M Breckwoldt
January 1972,
Endocrinology,
F Peters, and
M Lummerich, and
M Breckwoldt
June 1977,
Geburtshilfe und Frauenheilkunde,
F Peters, and
M Lummerich, and
M Breckwoldt
November 1979,
British journal of obstetrics and gynaecology,
F Peters, and
M Lummerich, and
M Breckwoldt
November 1975,
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F Peters, and
M Lummerich, and
M Breckwoldt
April 1969,
Endocrinology,
F Peters, and
M Lummerich, and
M Breckwoldt
January 1985,
Zentralblatt fur Gynakologie,
F Peters, and
M Lummerich, and
M Breckwoldt
October 1975,
British medical journal,
