Pyrido(2,3-d)pyrimidines. 3. Synthesis of some 8-( -D-ribofuranosyl)pyrido(2,3-d)pyrimidines structurally related to the antibiotic sangivamycin.
1972
B H Rizkalla, and
A D Broom
UI
MeSH Term
Description
Entries
D008956
Models, Chemical
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Chemical Models,Chemical Model,Model, Chemical
D011725
Pyridines
Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.
D011743
Pyrimidines
A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.
D011758
Pyrroles
Azoles of one NITROGEN and two double bonds that have aromatic chemical properties.
Pyrrole
D003500
Cyclization
Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Cyclizations
D000903
Antibiotics, Antineoplastic
Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms.
Nucleosides in which the purine or pyrimidine base is combined with ribose. (Dorland, 28th ed)
D013329
Structure-Activity Relationship
The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.