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The morphological and functional changes in the thyroid tissue of white rats injected lithium chloride at doses 0.5 mekv/kg and 1.0 mekv/kg (groups 1 and 2, respectively) during three weeks were studied by the radiometric, histological and biochemical methods. The radiometric, histological and biochemical methods. The inhibitory action of lithium chloride on hormonogenesis in the thyroid gland and secretion of thyroid hormones into the blood was proved to be directly related to the lithium dose and concentration in the blood. The data of intravital radiometric and morphological analysis of the organs of the 1st group animals suggest some activization of the gland function, with the secretion of the hormones into the blood being suppressed. Increased concentration of the drug inhibits hormonogenesis and secretion of thyroid hormones into the blood.
V A Glumova, and
N M Petrov, and
V N Markov
January 1981,
Endocrinologie,
V A Glumova, and
N M Petrov, and
V N Markov
January 1972,
Comptes rendus des seances de la Societe de biologie et de ses filiales,
V A Glumova, and
N M Petrov, and
V N Markov
June 1977,
Biulleten' eksperimental'noi biologii i meditsiny,
V A Glumova, and
N M Petrov, and
V N Markov
January 1976,
Farmakologiia i toksikologiia,
V A Glumova, and
N M Petrov, and
V N Markov
January 1966,
Voprosy pitaniia,
V A Glumova, and
N M Petrov, and
V N Markov
September 1968,
Ugeskrift for laeger,
V A Glumova, and
N M Petrov, and
V N Markov
January 1965,
Voprosy pitaniia,
V A Glumova, and
N M Petrov, and
V N Markov
May 1966,
Toxicology and applied pharmacology,
V A Glumova, and
N M Petrov, and
V N Markov
January 1963,
Problemy endokrinologii i gormonoterapii,
V A Glumova, and
N M Petrov, and
V N Markov
January 1972,
Eksperimentalna meditsina i morfologiia,
