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Myoblasts cultivated in vitro will undergo terminal differentiation to form muscle fibres. Teratoma derived mouse cell lines, a pluripotent primitive line, and a muscle cell line, provide a possibility for comparing RNA populations in an early precursor cell with those in committed myoblasts and differentiated myotubes. Molecular hybridization analyses led to the conclusion that new RNA sequences appear in the cytoplasm during muscle differentiation. Such muscle specific sequences are not detectable in the nuclear RNA of myoblasts or primitive cells. Studies of protein synthesis during terminal myogenesis indicate co-ordinate expression of the muscle contractile proteins. These represent distinct isozymes, distinguishable from the contractile proteins of other cell types. In the case of myosin light chains isozymic transitions between different muscle forms have been identified during early development.
F Gros, and
N Affara, and
M E Buckingham, and
M Jacquet, and
R G Whalen, and
P Daubas, and
J C Lelong, and
D Caput
May 1978,
The Biochemical journal,
F Gros, and
N Affara, and
M E Buckingham, and
M Jacquet, and
R G Whalen, and
P Daubas, and
J C Lelong, and
D Caput
January 1990,
Comparative biochemistry and physiology. B, Comparative biochemistry,
F Gros, and
N Affara, and
M E Buckingham, and
M Jacquet, and
R G Whalen, and
P Daubas, and
J C Lelong, and
D Caput
January 1969,
Current topics in developmental biology,
F Gros, and
N Affara, and
M E Buckingham, and
M Jacquet, and
R G Whalen, and
P Daubas, and
J C Lelong, and
D Caput
January 1964,
Clinical pharmacology and therapeutics,
F Gros, and
N Affara, and
M E Buckingham, and
M Jacquet, and
R G Whalen, and
P Daubas, and
J C Lelong, and
D Caput
May 1976,
Journal of gerontology,
F Gros, and
N Affara, and
M E Buckingham, and
M Jacquet, and
R G Whalen, and
P Daubas, and
J C Lelong, and
D Caput
January 1973,
Advances in morphogenesis,
F Gros, and
N Affara, and
M E Buckingham, and
M Jacquet, and
R G Whalen, and
P Daubas, and
J C Lelong, and
D Caput
January 1971,
Advances in clinical chemistry,
F Gros, and
N Affara, and
M E Buckingham, and
M Jacquet, and
R G Whalen, and
P Daubas, and
J C Lelong, and
D Caput
April 1953,
Bollettino della Societa italiana di biologia sperimentale,
F Gros, and
N Affara, and
M E Buckingham, and
M Jacquet, and
R G Whalen, and
P Daubas, and
J C Lelong, and
D Caput
October 1983,
Cancer research,
F Gros, and
N Affara, and
M E Buckingham, and
M Jacquet, and
R G Whalen, and
P Daubas, and
J C Lelong, and
D Caput
January 2002,
Advances in biochemical engineering/biotechnology,
