-transparent.png){kind=logo}
Twenty-six untreated patients with chronic persistent hepatitis were followed prospectively for one to 17 years (mean 5.6 years). The patients developed no clinical features of chronic liver disease. Raised serum transaminase levels were usually, but not consistently, the only biochemical abnormality; gamma globulin values were normal. Serum markers of past or present hepatitis B infection were found initially in 14 patients: another two developed markers during their follow-up. Nine patients progressed to a mild or moderate chronic active hepatitis as shown by serial needle liver biopsies but there was no evidence of cirrhosis. This progression was not associated with any clinical or biochemical deterioration. Seven of these patients had presented with insidious symptoms, seven had serum markers of hepatitis B infection, and the four who were HBsAg positive had relatively lower serum HBsAg concentrations than did those patients who continued with chronic persistent hepatitis.
R G Chadwick, and
J Galizzi, and
J Heathcote, and
T Lyssiotis, and
B J Cohen, and
P J Scheuer, and
S Sherlock
August 1989,
Archives of disease in childhood,
R G Chadwick, and
J Galizzi, and
J Heathcote, and
T Lyssiotis, and
B J Cohen, and
P J Scheuer, and
S Sherlock
January 1981,
Verhandlungen der Deutschen Gesellschaft fur Pathologie,
R G Chadwick, and
J Galizzi, and
J Heathcote, and
T Lyssiotis, and
B J Cohen, and
P J Scheuer, and
S Sherlock
September 1988,
Journal of adolescent health care : official publication of the Society for Adolescent Medicine,
R G Chadwick, and
J Galizzi, and
J Heathcote, and
T Lyssiotis, and
B J Cohen, and
P J Scheuer, and
S Sherlock
October 2022,
Clinics and research in hepatology and gastroenterology,
R G Chadwick, and
J Galizzi, and
J Heathcote, and
T Lyssiotis, and
B J Cohen, and
P J Scheuer, and
S Sherlock
November 1999,
Journal of viral hepatitis,
R G Chadwick, and
J Galizzi, and
J Heathcote, and
T Lyssiotis, and
B J Cohen, and
P J Scheuer, and
S Sherlock
April 1979,
Journal of clinical pathology,
R G Chadwick, and
J Galizzi, and
J Heathcote, and
T Lyssiotis, and
B J Cohen, and
P J Scheuer, and
S Sherlock
April 1985,
Revista espanola de las enfermedades del aparato digestivo,
R G Chadwick, and
J Galizzi, and
J Heathcote, and
T Lyssiotis, and
B J Cohen, and
P J Scheuer, and
S Sherlock
May 1983,
Revista medica de Chile,
R G Chadwick, and
J Galizzi, and
J Heathcote, and
T Lyssiotis, and
B J Cohen, and
P J Scheuer, and
S Sherlock
June 1988,
Liver,
R G Chadwick, and
J Galizzi, and
J Heathcote, and
T Lyssiotis, and
B J Cohen, and
P J Scheuer, and
S Sherlock
January 2015,
GE Portuguese journal of gastroenterology,
