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The ventilatory response to carbon dioxide, using the rebreathing technique, was investigated in 5 healthy nonsmoker volunteers, without obstructive bronchopathy. The administration of propranolol (20 mg) in a single oral dose did not produce significant modifications of the slopes of the response curves, but caused a significant increase of the intercept of the curves (p less than 0.05). Since no changes of the spirographic values were noted, the results obtained were attributed to a decrease of ventilation. It is concluded that propranolol, even at the dose of 20 mg, is able to induce a depression of the respiratory center, concomitant with significant reduction of heart rate and arterial blood pressure.
E Bosisio, and
M Sergi, and
R Sega, and
A Libretti
January 1983,
The Indian journal of chest diseases & allied sciences,
E Bosisio, and
M Sergi, and
R Sega, and
A Libretti
May 1966,
Canadian journal of physiology and pharmacology,
E Bosisio, and
M Sergi, and
R Sega, and
A Libretti
November 1976,
British medical journal,
E Bosisio, and
M Sergi, and
R Sega, and
A Libretti
April 1961,
Diseases of the chest,
E Bosisio, and
M Sergi, and
R Sega, and
A Libretti
January 1925,
The Journal of experimental medicine,
E Bosisio, and
M Sergi, and
R Sega, and
A Libretti
January 1980,
Respiration; international review of thoracic diseases,
E Bosisio, and
M Sergi, and
R Sega, and
A Libretti
September 1978,
Clinical science and molecular medicine,
E Bosisio, and
M Sergi, and
R Sega, and
A Libretti
January 1967,
Nature,
E Bosisio, and
M Sergi, and
R Sega, and
A Libretti
September 1960,
Journal of applied physiology,
E Bosisio, and
M Sergi, and
R Sega, and
A Libretti
January 1975,
The Journal of physiology,
