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Erythropoiesis was evaluated in 37 patients with sickle cell anaemia, 26 of them children under 12 years of age. Mean haemoglobin, haematocrit, reticulocyte, and erythropoietin levels were similar for 11 who were asymptomatic, 11 with infections, and 12 in vaso-occlusive crisis. Mean haemoglobin, haematocrit, and reticulocyte values were significantly lower and the mean erythropoietin level significantly higher for three patients in aplastic crisis. Reticulocyte counts reflected erythropoietic activity during the asymptomatic state but were variable during infection and crisis. No erythropoietic inhibitory activity was found in any of the four clinical states. It has been suggested that erythropoietin production decreases during infection. Patients in this study responded appropriately to stress, showing no decrease in erythropoietic activity during acute infection or crisis.
T B Haddy, and
J M Lusher, and
S Hendricks, and
B K Trosko
August 2018,
British journal of haematology,
T B Haddy, and
J M Lusher, and
S Hendricks, and
B K Trosko
March 1961,
British medical journal,
T B Haddy, and
J M Lusher, and
S Hendricks, and
B K Trosko
August 1975,
East African medical journal,
T B Haddy, and
J M Lusher, and
S Hendricks, and
B K Trosko
May 1961,
Lancet (London, England),
T B Haddy, and
J M Lusher, and
S Hendricks, and
B K Trosko
March 2012,
British journal of hospital medicine (London, England : 2005),
T B Haddy, and
J M Lusher, and
S Hendricks, and
B K Trosko
September 1983,
British medical journal (Clinical research ed.),
T B Haddy, and
J M Lusher, and
S Hendricks, and
B K Trosko
March 1981,
Lancet (London, England),
T B Haddy, and
J M Lusher, and
S Hendricks, and
B K Trosko
February 1989,
Postgraduate medical journal,
T B Haddy, and
J M Lusher, and
S Hendricks, and
B K Trosko
December 1994,
The Central African journal of medicine,
T B Haddy, and
J M Lusher, and
S Hendricks, and
B K Trosko
June 1980,
Indian pediatrics,
