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The report pertains to some data on the cholinesterase activity in the blood serum and CSF of 62 patients with epilepsy, in correlation with different clinical characteristics (the severity of the disease, the character of the EEG, frequency of seizures, treatment efficacy, etc). In 86,8% of the cases there was a significant increase in the activity of serum cholinesterase. Increased cholinesterase activity correlated only with pronounced pathological changes in the EEG (reverse correlation) and the efficacy of treatment (direct correlation). After surgical treatment of 9 cases there was a drop in the cholinesterase activity of the blood serum and CSF, which correlated with an improvement in the general state of the patients. On the basis of personal experience, as well as literary data, it is assumed that an increase in the cholinesterase activity in epileptic patients is not related to the main etiological factors of this disease but is rather a secondary change, a peculiar "symptom" of the disease.
N G Sergienko, and
A Gonzalez-Quevedo, and
N Gonzalez, and
L Simón y Canón, and
G Marin
June 1950,
Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali,
N G Sergienko, and
A Gonzalez-Quevedo, and
N Gonzalez, and
L Simón y Canón, and
G Marin
September 1973,
Kardiologiia,
N G Sergienko, and
A Gonzalez-Quevedo, and
N Gonzalez, and
L Simón y Canón, and
G Marin
January 1972,
Zhurnal eksperimental'noi i klinicheskoi meditsiny,
N G Sergienko, and
A Gonzalez-Quevedo, and
N Gonzalez, and
L Simón y Canón, and
G Marin
January 1972,
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952),
N G Sergienko, and
A Gonzalez-Quevedo, and
N Gonzalez, and
L Simón y Canón, and
G Marin
January 1986,
Klinicheskaia meditsina,
N G Sergienko, and
A Gonzalez-Quevedo, and
N Gonzalez, and
L Simón y Canón, and
G Marin
October 1976,
Vestnik dermatologii i venerologii,
N G Sergienko, and
A Gonzalez-Quevedo, and
N Gonzalez, and
L Simón y Canón, and
G Marin
October 1954,
Archives internationales de pharmacodynamie et de therapie,
N G Sergienko, and
A Gonzalez-Quevedo, and
N Gonzalez, and
L Simón y Canón, and
G Marin
July 1959,
Biulleten' eksperimental'noi biologii i meditsiny,
N G Sergienko, and
A Gonzalez-Quevedo, and
N Gonzalez, and
L Simón y Canón, and
G Marin
January 1957,
Duodecim; laaketieteellinen aikakauskirja,
N G Sergienko, and
A Gonzalez-Quevedo, and
N Gonzalez, and
L Simón y Canón, and
G Marin
June 1971,
Pediatriia,
