Surgical stimulation of the uveoscleral outflow. Experimental studies on enucleated human eyes. 1979

A P Nesterov, and Y E Batmanov, and I N Cherkasova, and E A Egorov

Six series of experiments were performed on 45 isolated cadaver eyes. In the first series, the outflow facility of the human sclera was measured, in the others, five surgical techniques for stimulating the uveo-scleral outflow were evaluted with the help of a constant pressure perfusion technique. It was found that the scleral C-value was pressure independent and its average value was equal to 0.0036 mm3/min/mmHg per 1 cm2 (100 mm2) of scleral surface. After the implantation of a scleral strip into the supra-uveal space, the mean increase in the total C-value was 23% of its initial value, ranging from 7 to 35%. After cyclodialysis the C-value increment varied from 17% to 66%, averaging 30%. The average increase in the outflow facility amounted to 60% (range 24--96%) in those cases where implantation of the scleral strip in the suprauveal space was combined with cyclodialysis. After implantation of a scleral strip, combined with subscleral sinusotomy, the C-value increment varied from 18 to 71%, averaging 41%. After cyclodialysis combined with goniospasis, the mean increase in the outflow facility coefficient was 62% (range 43%--108%).

UI MeSH Term Description Entries
D008722 Methods A series of steps taken in order to conduct research. Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D009885 Ophthalmology A surgical specialty concerned with the structure and function of the eye and the medical and surgical treatment of its defects and diseases. Ocular Surgery,Ocular Surgeries,Surgery, Ocular
D005901 Glaucoma An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed) Glaucomas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012590 Sclera The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the CANAL OF SCHLEMM. (From Cline et al., Dictionary of Visual Science, 4th ed) Scleral Spur,Scleral Spurs,Scleras
D014602 Uvea The pigmented vascular coat of the eyeball, consisting of the CHOROID; CILIARY BODY; and IRIS, which are continuous with each other. (Cline et al., Dictionary of Visual Science, 4th ed) Uveas
D066298 In Vitro Techniques Methods to study reactions or processes taking place in an artificial environment outside the living organism. In Vitro Test,In Vitro Testing,In Vitro Tests,In Vitro as Topic,In Vitro,In Vitro Technique,In Vitro Testings,Technique, In Vitro,Techniques, In Vitro,Test, In Vitro,Testing, In Vitro,Testings, In Vitro,Tests, In Vitro,Vitro Testing, In

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