Identification and differentiation of surgically correctable hypertension due to primary aldosteronism. 1979

S M Herf, and D C Teates, and C J Tegtmeyer, and E D Vaughan, and C R Ayers, and R M Carey

During a protocol study for the evaluation of patients with primary aldosteronism, a variety of diagnostic studies were employed in an attempt to identify patients with primary aldosteronism and to differentiate patients with adrenal adenoma from patients with idiopathic adrenal hyperplasia. In this study, we are able to demonstrate the utility of (1) absent postural increase in plasma aldosterone concentration, (2) adrenal scanning and (3) normalization of blood pressure with spironolactone therapy in identifying patients with primary aldosterone excess who have an adrenal adenoma, surgical removal of which results in eliminating their hypertension.

UI MeSH Term Description Entries
D006965 Hyperplasia An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells. Hyperplasias
D006973 Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. Blood Pressure, High,Blood Pressures, High,High Blood Pressure,High Blood Pressures
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006929 Hyperaldosteronism A condition caused by the overproduction of ALDOSTERONE. It is characterized by sodium retention and potassium excretion with resultant HYPERTENSION and HYPOKALEMIA. Aldosteronism,Conn Syndrome,Conn's Syndrome,Primary Hyperaldosteronism,Conns Syndrome,Hyperaldosteronism, Primary,Syndrome, Conn,Syndrome, Conn's
D000236 Adenoma A benign epithelial tumor with a glandular organization. Adenoma, Basal Cell,Adenoma, Follicular,Adenoma, Microcystic,Adenoma, Monomorphic,Adenoma, Papillary,Adenoma, Trabecular,Adenomas,Adenomas, Basal Cell,Adenomas, Follicular,Adenomas, Microcystic,Adenomas, Monomorphic,Adenomas, Papillary,Adenomas, Trabecular,Basal Cell Adenoma,Basal Cell Adenomas,Follicular Adenoma,Follicular Adenomas,Microcystic Adenoma,Microcystic Adenomas,Monomorphic Adenoma,Monomorphic Adenomas,Papillary Adenoma,Papillary Adenomas,Trabecular Adenoma,Trabecular Adenomas
D000310 Adrenal Gland Neoplasms Tumors or cancer of the ADRENAL GLANDS. Adrenal Cancer,Adrenal Gland Cancer,Adrenal Neoplasm,Cancer of the Adrenal Gland,Neoplasms, Adrenal Gland,Adrenal Cancers,Adrenal Gland Cancers,Adrenal Gland Neoplasm,Adrenal Neoplasms,Cancer, Adrenal,Cancer, Adrenal Gland,Cancers, Adrenal,Cancers, Adrenal Gland,Neoplasm, Adrenal,Neoplasm, Adrenal Gland,Neoplasms, Adrenal
D000311 Adrenal Glands A pair of glands located at the cranial pole of each of the two KIDNEYS. Each adrenal gland is composed of two distinct endocrine tissues with separate embryonic origins, the ADRENAL CORTEX producing STEROIDS and the ADRENAL MEDULLA producing NEUROTRANSMITTERS. Adrenal Gland,Gland, Adrenal,Glands, Adrenal
D000315 Adrenalectomy Excision of one or both adrenal glands. (From Dorland, 28th ed) Adrenalectomies

Related Publications

S M Herf, and D C Teates, and C J Tegtmeyer, and E D Vaughan, and C R Ayers, and R M Carey
September 2006, Best practice & research. Clinical endocrinology & metabolism,
S M Herf, and D C Teates, and C J Tegtmeyer, and E D Vaughan, and C R Ayers, and R M Carey
November 1981, Archives of internal medicine,
S M Herf, and D C Teates, and C J Tegtmeyer, and E D Vaughan, and C R Ayers, and R M Carey
February 2012, Journal of hypertension,
S M Herf, and D C Teates, and C J Tegtmeyer, and E D Vaughan, and C R Ayers, and R M Carey
May 2010, Orphanet journal of rare diseases,
S M Herf, and D C Teates, and C J Tegtmeyer, and E D Vaughan, and C R Ayers, and R M Carey
April 2004, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
S M Herf, and D C Teates, and C J Tegtmeyer, and E D Vaughan, and C R Ayers, and R M Carey
June 2002, Pathology,
S M Herf, and D C Teates, and C J Tegtmeyer, and E D Vaughan, and C R Ayers, and R M Carey
April 2005, Revue medicale de Liege,
S M Herf, and D C Teates, and C J Tegtmeyer, and E D Vaughan, and C R Ayers, and R M Carey
September 1977, Mayo Clinic proceedings,
S M Herf, and D C Teates, and C J Tegtmeyer, and E D Vaughan, and C R Ayers, and R M Carey
September 1973, The Journal of the Maine Medical Association,
S M Herf, and D C Teates, and C J Tegtmeyer, and E D Vaughan, and C R Ayers, and R M Carey
March 2004, The Journal of clinical endocrinology and metabolism,
Copied contents to your clipboard!