BIOMAT Database Logo BIOMAT Database Logo

Kinetics of the lethal effect of actinomycin D on normal and leukemic cells. 1973

F Valeriote, and T Vietti, and S Tolen

UI MeSH Term Description Entries
D007700 Kinetics The rate dynamics in chemical or physical systems.
D007942 Leukemia, Experimental Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues. Experimental Leukemia,Experimental Leukemias,Leukemia Model, Animal,Leukemias, Experimental,Animal Leukemia Model,Animal Leukemia Models,Leukemia Models, Animal
D008806 Mice, Inbred AKR An inbred strain of mouse that is widely used in IMMUNOLOGY studies and cancer research. Mice, AKR,Mouse, AKR,Mouse, Inbred AKR,AKR Mice,AKR Mice, Inbred,AKR Mouse,AKR Mouse, Inbred,Inbred AKR Mice,Inbred AKR Mouse
D009368 Neoplasm Transplantation Experimental transplantation of neoplasms in laboratory animals for research purposes. Transplantation, Neoplasm,Neoplasm Transplantations,Transplantations, Neoplasm
D002455 Cell Division The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION. M Phase,Cell Division Phase,Cell Divisions,Division Phase, Cell,Division, Cell,Divisions, Cell,M Phases,Phase, Cell Division,Phase, M,Phases, M
D002460 Cell Line Established cell cultures that have the potential to propagate indefinitely. Cell Lines,Line, Cell,Lines, Cell
D003609 Dactinomycin A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015) Actinomycin,Actinomycin D,Meractinomycin,Cosmegen,Cosmegen Lyovac,Lyovac-Cosmegen,Lyovac Cosmegen,Lyovac, Cosmegen,LyovacCosmegen
D004305 Dose-Response Relationship, Drug The relationship between the dose of an administered drug and the response of the organism to the drug. Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D006412 Hematopoietic Stem Cells Progenitor cells from which all blood cells derived. They are found primarily in the bone marrow and also in small numbers in the peripheral blood. Colony-Forming Units, Hematopoietic,Progenitor Cells, Hematopoietic,Stem Cells, Hematopoietic,Hematopoietic Progenitor Cells,Cell, Hematopoietic Progenitor,Cell, Hematopoietic Stem,Cells, Hematopoietic Progenitor,Cells, Hematopoietic Stem,Colony Forming Units, Hematopoietic,Colony-Forming Unit, Hematopoietic,Hematopoietic Colony-Forming Unit,Hematopoietic Colony-Forming Units,Hematopoietic Progenitor Cell,Hematopoietic Stem Cell,Progenitor Cell, Hematopoietic,Stem Cell, Hematopoietic,Unit, Hematopoietic Colony-Forming,Units, Hematopoietic Colony-Forming
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

Related Publications

F Valeriote, and T Vietti, and S Tolen
Effect of actinomycin D on tissue cultures of normal and neoplastic cells.
August 1958, Journal of the National Cancer Institute,
F Valeriote, and T Vietti, and S Tolen
The differential effect of actinomycin D in normal and virus-transformed cells.
April 1973, The Journal of cell biology,
F Valeriote, and T Vietti, and S Tolen
[Effect of actinomycin D on hematopoietic stem cells].
January 1981, Ontogenez,
F Valeriote, and T Vietti, and S Tolen
Effect of actinomycin D on immune antibody, normal antibody, and complement.
January 1966, Journal of bacteriology,
F Valeriote, and T Vietti, and S Tolen
Effect of actinomycin D and busulphan on stem cells in normal and Friend virus infected mice.
April 1979, Blut,
F Valeriote, and T Vietti, and S Tolen
Human leukemic cells. Actinomycin D-resistant biosynthesis of RNA by isolated nuclei.
December 1969, Experimental cell research,
F Valeriote, and T Vietti, and S Tolen
Commentary: effect of flavonoids on normal and leukemic cells.
June 2003, Leukemia research,
F Valeriote, and T Vietti, and S Tolen
The effect of actinomycin D on RNA metabolism in human cells.
January 2006, Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology,
F Valeriote, and T Vietti, and S Tolen
THE EFFECT OF ACTINOMYCIN D ON PREMITOTIC CELLS. LA-3132-MS.
September 1964, LA [reports]. U.S. Atomic Energy Commission,
F Valeriote, and T Vietti, and S Tolen
Human leukemic cells: properties of an RNA synthesized in the presence of actinomycin D.
May 1974, Experimental cell research,
Copied contents to your clipboard!