Biomaterial Database

Efficacy of injectable and tablet formulations of praziquantel against immature Echinococcus granulosus. 1979

F L Anderson, and G A Conder, and W P Marsland

Efficacy of an injectable formulation of praziquantel (given intramuscularly or subcutaneously at a dosage level of 5 mg/kg of body weight) or a tablet formulation (5 mg/kg) against immature Echinococcus granulosus was studied in experimentally infected dogs. The compound was efficacious (100% clearance) if injected via either route or if administered orally.

UI	MeSH Term	Description	Entries
D007273	Injections, Intramuscular	Forceful administration into a muscle of liquid medication, nutrient, or other fluid through a hollow needle piercing the muscle and any tissue covering it.	Intramuscular Injections,Injection, Intramuscular,Intramuscular Injection
D007279	Injections, Subcutaneous	Forceful administration under the skin of liquid medication, nutrient, or other fluid through a hollow needle piercing the skin.	Subcutaneous Injections,Injection, Subcutaneous,Subcutaneous Injection
D007546	Isoquinolines	A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. (From Stedman, 25th ed)
D008297	Male		Males
D011719	Pyrazines	A heterocyclic aromatic organic compound with the chemical formula C4H4N2.	Pyrazine
D004283	Dog Diseases	Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.	Canine Diseases,Canine Disease,Disease, Canine,Disease, Dog,Diseases, Canine,Diseases, Dog,Dog Disease
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D004443	Echinococcosis	An infection caused by the infestation of the larval form of tapeworms of the genus Echinococcus. The liver, lungs, and kidney are the most common areas of infestation.	Cystic Echinococcosis,Cysts, Hydatid,Hydatid Cyst,Hydatidosis,Echinococcus Granulosus Infection,Echinococcus Infection,Hydatid Disease,Cyst, Hydatid,Cystic Echinococcoses,Echinococcoses,Echinococcoses, Cystic,Echinococcosis, Cystic,Echinococcus Granulosus Infections,Echinococcus Infections,Granulosus Infection, Echinococcus,Granulosus Infections, Echinococcus,Hydatid Cysts,Hydatid Diseases,Hydatidoses,Infection, Echinococcus,Infection, Echinococcus Granulosus,Infections, Echinococcus Granulosus
D005260	Female		Females
D000284	Administration, Oral	The giving of drugs, chemicals, or other substances by mouth.	Drug Administration, Oral,Administration, Oral Drug,Oral Administration,Oral Drug Administration,Administrations, Oral,Administrations, Oral Drug,Drug Administrations, Oral,Oral Administrations,Oral Drug Administrations