BIOMAT Database Logo BIOMAT Database Logo

Enhanced radiosensitivity of cultured fibroblasts from ataxia telangiectasia heterozygotes manifested by defective colony-forming ability and reduced DNA repair replication after hypoxic gamma-irradiation. 1979

M C Paterson, and A K Anderson, and B P Smith, and P J Smith

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010100 Oxygen An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. Dioxygen,Oxygen-16,Oxygen 16
D002455 Cell Division The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION. M Phase,Cell Division Phase,Cell Divisions,Division Phase, Cell,Division, Cell,Divisions, Cell,M Phases,Phase, Cell Division,Phase, M,Phases, M
D002470 Cell Survival The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability. Cell Viability,Cell Viabilities,Survival, Cell,Viabilities, Cell,Viability, Cell
D002478 Cells, Cultured Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others. Cultured Cells,Cell, Cultured,Cultured Cell
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D004260 DNA Repair The removal of DNA LESIONS and/or restoration of intact DNA strands without BASE PAIR MISMATCHES, intrastrand or interstrand crosslinks, or discontinuities in the DNA sugar-phosphate backbones. DNA Damage Response
D004261 DNA Replication The process by which a DNA molecule is duplicated. Autonomous Replication,Replication, Autonomous,Autonomous Replications,DNA Replications,Replication, DNA,Replications, Autonomous,Replications, DNA

Related Publications

M C Paterson, and A K Anderson, and B P Smith, and P J Smith
Cellular hypersensitivity to chronic gamma-radiation in cultured fibroblasts from ataxia-telangiectasia heterozygotes.
January 1985, Kroc Foundation series,
M C Paterson, and A K Anderson, and B P Smith, and P J Smith
Enhanced radiosensitivity and defective DNA repair in cultured fibroblasts derived from Rothmund Thomson syndrome patients.
May 1982, Mutation research,
M C Paterson, and A K Anderson, and B P Smith, and P J Smith
Decreased DNA repair synthesis and defective colony-forming ability of ataxia telangiectasia fibroblast cell strains treated with N-methyl-N'-nitro-N-nitrosoguanidine.
April 1980, Cancer research,
M C Paterson, and A K Anderson, and B P Smith, and P J Smith
Ataxia telangiectasia: an anomaly in DNA replication after irradiation.
March 1981, Nucleic acids research,
M C Paterson, and A K Anderson, and B P Smith, and P J Smith
Impaired colony-forming ability following gamma irradiation of skin fibroblasts from tuberous sclerosis patients.
May 1982, Radiation research,
M C Paterson, and A K Anderson, and B P Smith, and P J Smith
Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate gamma-irradiation as assayed by pulsed field gel electrophoresis.
November 1991, International journal of radiation biology,
M C Paterson, and A K Anderson, and B P Smith, and P J Smith
Comparative human cellular radiosensitivity: II. The survival following gamma-irradiation of unstimulated (G0) T-lymphocytes, T-lymphocyte lines, lymphoblastoid cell lines and fibroblasts from normal donors, from ataxia-telangiectasia patients and from ataxia-telangiectasia heterozygotes.
December 1988, International journal of radiation biology,
M C Paterson, and A K Anderson, and B P Smith, and P J Smith
Effect of aphidicolin on de novo DNA synthesis, DNA repair and cytotoxicity in gamma-irradiated human fibroblasts. Implications for the enhanced radiosensitivity in ataxia telangiectasia.
January 1983, Biochimica et biophysica acta,
M C Paterson, and A K Anderson, and B P Smith, and P J Smith
Defective DNA repair replication in xeroderma pigmentosum fibroblasts and DNA repair of somatic cell hybrids after UV irradiation.
September 1975, The Tohoku journal of experimental medicine,
M C Paterson, and A K Anderson, and B P Smith, and P J Smith
Colony-forming ability of ultraviolet-irradiated xeroderma pigmentosum fibroblasts from different DNA repair complementation groups.
August 1976, Biochimica et biophysica acta,
Copied contents to your clipboard!