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The effect of intravenous somatostatin on blood levels of metabolites and hormones has been examined in normal subjects who performed a 30-minute period of bicycle exercises at 70% maximal exercise capacity. The results have been compared with control studies in the same subjects. Measurements were made of blood levels of lactate, glucose, free fatty acids, glycerol, acetoacetate, 3-hydroxybutyrate, insulin, glucagon, growth hormone (hGH) and prolactin. Growth hormone and glucagon release were suppressed during exercise with somatostatin and there was a subsequent elevation during recovery. There was slight post-exercise depression of insulin, but no alteration of plasma prolactin secretion. Blood glucose was reduced during exercise with somatostatin and increased during recovery. The elevation of ketone bodies after exercise was greater in the investigation with somatostatin, but there were no significant changes in other metabolites. Somatostatin, although causing inhibition of hGH release, appeared to have no significant effect upon fatty acid mobilization during exercise.
R J Chalmers, and
S R Bloom, and
G Duncan, and
R H Johnson, and
W R Sulaiman
December 1989,
Nihon Sanka Fujinka Gakkai zasshi,
R J Chalmers, and
S R Bloom, and
G Duncan, and
R H Johnson, and
W R Sulaiman
January 1990,
Metabolism: clinical and experimental,
R J Chalmers, and
S R Bloom, and
G Duncan, and
R H Johnson, and
W R Sulaiman
July 1983,
Journal of neurology, neurosurgery, and psychiatry,
R J Chalmers, and
S R Bloom, and
G Duncan, and
R H Johnson, and
W R Sulaiman
March 1999,
Journal of physiology and biochemistry,
R J Chalmers, and
S R Bloom, and
G Duncan, and
R H Johnson, and
W R Sulaiman
December 1968,
Lancet (London, England),
R J Chalmers, and
S R Bloom, and
G Duncan, and
R H Johnson, and
W R Sulaiman
October 1976,
Diabetologia,
R J Chalmers, and
S R Bloom, and
G Duncan, and
R H Johnson, and
W R Sulaiman
November 2021,
European journal of applied physiology,
R J Chalmers, and
S R Bloom, and
G Duncan, and
R H Johnson, and
W R Sulaiman
January 1979,
Acta diabetologica latina,
R J Chalmers, and
S R Bloom, and
G Duncan, and
R H Johnson, and
W R Sulaiman
May 1982,
Wiener klinische Wochenschrift,
R J Chalmers, and
S R Bloom, and
G Duncan, and
R H Johnson, and
W R Sulaiman
February 1996,
Journal of applied physiology (Bethesda, Md. : 1985),
