[Rifampicin levels in blood, urine and kidney tissue in patients with renal tuberculosis].
1973
T P Mochalova, and
S S Kanevskaia, and
N K Danilova
UI
MeSH Term
Description
Entries
D007668
Kidney
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
Kidneys
D008297
Male
Males
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012293
Rifampin
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)