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The Limulus test and pyrogen testing. 1979

N Diding

UI MeSH Term Description Entries
D008033 Limulus Test Sensitive method for detection of bacterial endotoxins and endotoxin-like substances that depends on the in vitro gelation of Limulus amebocyte lysate (LAL), prepared from the circulating blood (amebocytes) of the horseshoe crab, by the endotoxin or related compound. Used for detection of endotoxin in body fluids and parenteral pharmaceuticals. Limulus Tests,Test, Limulus,Tests, Limulus
D011749 Pyrogens Substances capable of increasing BODY TEMPERATURE and cause FEVER and may be used for FEVER THERAPY. They may be of microbial origin, often POLYSACCHARIDES, and may contaminate distilled water. Pyrogen
D004731 Endotoxins Toxins closely associated with the living cytoplasm or cell wall of certain microorganisms, which do not readily diffuse into the culture medium, but are released upon lysis of the cells. Endotoxin
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

Related Publications

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[Pyrogen testing in vitro using the Limulus test].
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Limulus lysate testing of biologics requirements for the rabbit pyrogen test.
January 1979, Progress in clinical and biological research,
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Automation of Limulus amoebocyte lysate pyrogen testing.
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The Limulus test for in vitro pyrogen detection.
July 1974, American journal of hospital pharmacy,
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[Pyrogen test and Limulus test--on the relation between the 2 tests].
January 1982, Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences,
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[Comparison of the Limulus test with the pyrogen test in rabbits].
January 1980, Acta biologica et medica Germanica,
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The Limulus test for endotoxin (Pyrogen) in radiopharmaceuticals and biologicals.
January 1972, Bulletin of the Parenteral Drug Association,
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[Studies on the relationship between the pyrogen test and limulus test (author's transl)].
January 1980, Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences,
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A comparison between the Limulus amebocyte lysate test and the rabbit pyrogen test.
January 1979, Journal de pharmacie de Belgique,
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Utilization of the limulus amebocyte lysate test for pyrogen testing large volume parenterals, administration sets, and medical devices.
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