BIOMAT Database Logo BIOMAT Database Logo

Distribution of 1,6-dimethyl-3-carbethoxy-4-oxo-6,7,8,9-tetrahydrohomopyrimidazole-methylsulphate (MZ-144, Probon). 1973

K Magyar, and J Knoll

UI MeSH Term Description Entries
D007668 Kidney Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. Kidneys
D008099 Liver A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances. Livers
D008168 Lung Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood. Lungs
D008297 Male Males
D008431 Maternal-Fetal Exchange Exchange of substances between the maternal blood and the fetal blood at the PLACENTA via PLACENTAL CIRCULATION. The placental barrier excludes microbial or viral transmission. Transplacental Exposure,Exchange, Maternal-Fetal,Exposure, Transplacental,Maternal Fetal Exchange
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D009206 Myocardium The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow. Muscle, Cardiac,Muscle, Heart,Cardiac Muscle,Myocardia,Cardiac Muscles,Heart Muscle,Heart Muscles,Muscles, Cardiac,Muscles, Heart
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011744 Pyrimidinones Heterocyclic compounds known as 2-pyrimidones (or 2-hydroxypyrimidines) and 4-pyrimidones (or 4-hydroxypyrimidines) with the general formula C4H4N2O. Pyrimidinone,Pyrimidone,Pyrimidones
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon

Related Publications

K Magyar, and J Knoll
The pharmacology of 1,6-dimethyl-3-carbethoxy-4-oxo-6,7,8,9-tetrahydro-homopyrimidazol-methylsulphate (MZ-144), a new, potent, non-narcotic analgesic. 3. Analysis of the central and peripheric effects.
May 1971, Arzneimittel-Forschung,
K Magyar, and J Knoll
The pharmacology of 1,6-dimethyl-3-carbethoxy-4-oxo-6,7,8,9-tetrahydrohomopyrimidazol-methylsulphate (MZ-144), a new, potent, non-narcotic analgesic. II. Toxicity and analgetic effect of MZ-144 compared to narcotic and non-narcotic analgesics.
May 1971, Arzneimittel-Forschung,
K Magyar, and J Knoll
The pharmacology of 1,6-dimethyl-3-carbethoxy-4-oxo-6,7,8,9-tetrahydro-homopyrimidazol-methylsulphate (MZ-144), a new, potent, non narcotic analgesic. I. Some basic correlations between the chemical structure and activity of homopyrimidazol analgesics. Selection of MZ-144.
May 1971, Arzneimittel-Forschung,
K Magyar, and J Knoll
Clinical evaluation of the analgesic action of MZ-144 (Probon).
November 1972, International journal of clinical pharmacology, therapy and toxicology,
K Magyar, and J Knoll
Effect of MZ 144 (Probon) on respiratory acidosis of the aged.
January 1973, Therapia Hungarica (English edition),
K Magyar, and J Knoll
The fate of 2:4-dimethyl-3-carbethoxy-pyrrole-5-carboxylic acid and 2:4-dimethyl-5-carbethoxy-pyrrole-3-carboxylic acid in the rabbit.
January 1948, The Biochemical journal,
K Magyar, and J Knoll
Piperidinium 3-[(4-hydroxy-5-dimethyl-2-oxo-2H-chromen-3-yl)-phenylmethyl]-5,7-dimethyl-2-oxo-2H-chromen-4-olate.
July 2001, Acta crystallographica. Section C, Crystal structure communications,
K Magyar, and J Knoll
Ethyl 1,6-dimethyl-2-oxo-4-(quinolin-4-yl)-1,2,3,4-tetra-hydro-pyrimidine-5-carboxyl-ate.
June 2010, Acta crystallographica. Section E, Structure reports online,
K Magyar, and J Knoll
2-Methyl-4-oxo-6,7,8,9-tetrahydro-thieno[2',3':4,5]pyrimidino-[1,2-a]pyridine-3-carboxylic acid.
April 2011, Acta crystallographica. Section E, Structure reports online,
K Magyar, and J Knoll
N-(4-Fluorobenzyl)-3-hydroxy-9,9-dimethyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrazino[1,2-a]pyrimidine-2-carboxamides a novel class of potent HIV-1 integrase inhibitors.
August 2009, Bioorganic & medicinal chemistry letters,
Copied contents to your clipboard!